2,4-Difluoro-3-chlorobenzoic Acid CAS 154257-75-7
| CAS No. | 154257-75-7 |
| Molecular Formula | C7H3ClF2O2 |
| Molecular Weight | 192.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Difluoro-3-chlorobenzoic Acid (CAS 154257-75-7), molecular formula C7H3ClF2O2 and molecular weight 192.55 g/mol, is a CATO reference standard with documented purity and traceability.
2,4-Difluoro-3-chlorobenzoic Acid (C7H3ClF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,4-Difluoro-3-chlorobenzoic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClF2O2 |
| Molecular Weight | 192.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F/Cl-containing |
Related Difluoro Standards
- 3,5-Difluoro-2-hydroxybenzoyl chloride (CAS 1706461-06-4)
- 2,4-Difluoro-3-methoxybenzyl chloride (CAS 178974-99-7)
- 2,3-Difluoro-6-chlorophenylboronic acid (CAS 1310404-70-6)
- 1,11-Difluoro-undecane (CAS 1828-07-5)
- Methyl 4,4-difluoro-1-methylcyclohexanecarboxylate (CAS 1360568-90-6)
- methyl 2,2-difluoro-2-phenyl-acetate (CAS 56071-96-6)
- 7,7-Difluoro-6,7-dihydro-4H-pyrano[3,4-d]thiazol-2-amine (CAS 1391732-60-7)
- 2,2-Difluoro-2-(5-methylthiophen-3-yl)acetic acid (CAS 1462248-74-3)
Recommended Standards
- 2,6-Difluorophenyl carbonochloridate (CAS 1516039-72-7)
- 3-Chloro-4,5-difluorobenzoic acid (CAS 150444-95-4)
- 2-Chloro-3,5-difluorobenzoic acid (CAS 189024-26-8)
- 4-Chloro-2,3-difluorobenzoic acid (CAS 150444-94-3)
- 3-(3-Bromophenyl)-1H-pyrazole-4-carbonitrile (CAS 1170378-39-8)
- N-(3-Succinimidyloxy-carbonyl-phenyl)-methyl-4-(5'-(4''-methoxy-phenyl)-2'-oxazo 155862-95-6 Stain 7-I N-(3-Succinimidyloxy-carbonyl-phenyl)-methyl-4-(5'-(4''-methoxy-phenyl)-2'-oxazolyl)-pyridinium bromide (CAS 155862-95-6)
- 2-Methyl-4-azaindole (CAS 73177-35-2)
- 3-Ethoxy-5-(2,4,5-trichlorophenyl)-1H-1,2,4-triazole (CAS 62036-15-1)
- 7-Bromo-2-iodobenzo[d]thiazole (CAS 1175278-13-3)
- 1-(3-(Trifluoromethyl)phenyl)piperidin-4-one (CAS 147378-74-3)
- 2-(1-Aminocyclohexyl)-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 1334203-64-3)
- 11-Acetoxy-Δ9-tetrahydrocannabinol (CAS 26108-47-4)
- Ethyl 2-((1,3-dimethyl-2,4-dioxo-6-propyl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-5-yl)thio)acetate (CAS 900004-91-3)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com