(E)-3-(dimethylamino)-1-(3-(trifluoromethoxy)phenyl)prop-2-en-1-one CAS 154258-46-5
| CAS No. | 154258-46-5 |
| Molecular Formula | C12H12F3NO2 |
| Molecular Weight | 259.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 259.22 g/mol gives (E)-3-(dimethylamino)-1-(3-(trifluoromethoxy)phenyl)prop-2-en-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (E)-3-(dimethylamino)-1-(3-(trifluoromethoxy)phenyl)prop-2-en-1-one (CAS 154258-46-5), a certified reference material (molecular formula C12H12F3NO2, MW 259.22 g/mol) for analytical method development and quality control.
(E)-3-(dimethylamino)-1-(3-(trifluoromethoxy)phenyl)prop-2-en-1-one (C12H12F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12F3NO2 |
| Molecular Weight | 259.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
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- 1-[2-(dimethylamino)ethyl]-5-phenyl-1H-pyrazole-4-carboxylic acid (CAS 1283555-02-1)
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Recommended Standards
- 4-(Hydroxymethyl)-1-(3-(trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 1512199-31-3)
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- 6-Amino-3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 150439-90-0)
- 3-Nitro-N-(4-nitrophenyl)aniline (CAS 15979-87-0)
- Mabuterol-d9 (CAS 1246819-58-8)
- 2-(4-methoxy-3-propoxy-phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246765-89-7)
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- Ethyl 4-(ethylsulfonamido)benzoate (CAS 94523-92-9)
- 3-Amino-5-(isopropylcarbamoyl)phenylboronic acid (CAS 2096336-52-4)
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- 1H,1H,2H,2H-Perfluoro(11-methyldodecan-1-ol) (CAS 194427-39-9)
- Methyl (S)-2-(1,3-dioxoisoindolin-2-yl)-3-hydroxypropanoate (CAS 70494-26-7)
- 4-Nitro-1-Naphthol (CAS 605-62-9)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
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