1-(3-Chloro-4-fluorophenyl)-3-(dimethylamino)prop-2-en-1-one CAS 154258-48-7
| CAS No. | 154258-48-7 |
| Molecular Formula | C11H11ClFNO |
| Molecular Weight | 227.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(3-Chloro-4-fluorophenyl)-3-(dimethylamino)prop-2-en-1-one (CAS 154258-48-7) is a high-purity analytical reference standard with the molecular formula C11H11ClFNO and a molecular weight of 227.66 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-(3-Chloro-4-fluorophenyl)-3-(dimethylamino)prop-2-en-1-one is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 227.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-(3-Chloro-4-fluorophenyl)-3-(dimethylamino)prop-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11ClFNO |
| Molecular Weight | 227.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-chloro-N-cyclopropyl-2-(4-fluorophenyl)acetamide (CAS 1248663-82-2)
- 5-(2-Chloro-4-fluorophenoxy)pentanenitrile (CAS 1250074-05-5)
- (4-Chloro-2-fluorophenyl)(pyrrolidin-1-yl)methanone (CAS 1377899-61-0)
- 7-Chloro-1-ethyl-6-fluoro-2,3-dihydroquinolin-4(1H)-one (CAS 140700-97-6)
- 5-(4-Chloro-2-fluorophenoxy)pentanenitrile (CAS 1443333-47-8)
- 5-(3-Chloro-2-fluorophenoxy)pentanenitrile (CAS 1443342-58-2)
- 5-(2-Chloro-5-fluorophenoxy)pentanenitrile (CAS 1443347-92-9)
- 5-(3-Chloro-4-fluorophenoxy)pentanenitrile (CAS 1443351-13-0)
Recommended Standards
- 4-(Chloromethyl)-2-((2,2-difluoroethoxy)methyl)thiazole (CAS 1556789-20-8)
- 1-(5-Allyl-2-chloro-3-fluoropyridin-4-yl)prop-2-en-1-ol (CAS 2226541-27-9)
- 3-(4-chlorobenzenesulfonyl)prop-2-enenitrile (CAS 1012-71-1)
- 3-(3-Chlorophenyl)thiazolidine-2,4-dione (CAS 1013-68-9)
- 2,5-Bis(phenylethynyl)terephthalaldehyde (CAS 97094-35-4)
- 3-Chloropropionitrile (CAS 542-76-7)
- 2,5-Dichloro-n-(2,2,2-trifluoroethyl)pyrimidin-4-amine (CAS 1215034-20-0)
- (S)-1-[(S)-1-Phenylethyl]pyrrolidine-3-methanol (CAS 173724-95-3)
- Ethyl 5-bromo-6-hydroxynicotinate (CAS 169773-94-8)
- n-(1-Methoxypropan-2-yl)nonan-2-amine (CAS 1039932-16-5)
- (R)-6-(4-Bromophenyl)-4-((S)-1-phenylethyl)morpholin-3-one (CAS 920801-93-0)
- 2,4-Dichloro-6-fluorophenacyl chloride (CAS 1806276-84-5)
- Ethyl 5-hydroxy-3-isopropyl-1H-pyrazole-4-carboxylate (CAS 467248-40-4)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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