7-(Hydroxymethyl)-3H-pyrrolizin-3-one CAS 154367-62-1

Purity 97%+In StockPharmaceutical Standards
CAS No.154367-62-1
Molecular FormulaC8H7NO2
Molecular Weight149.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-(Hydroxymethyl)-3H-pyrrolizin-3-one CAS 154367-62-1 chemical structure

Description

The occurrence of 7-(Hydroxymethyl)-3H-pyrrolizin-3-one is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

7-(Hydroxymethyl)-3H-pyrrolizin-3-one (CAS 154367-62-1) is a high-purity analytical reference standard with the molecular formula C8H7NO2 and a molecular weight of 149.15 g/mol.

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 7-(Hydroxymethyl)-3H-pyrrolizin-3-one is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 149.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H7NO2
Molecular Weight149.15 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2001
Nitrogen Atoms1

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