(4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol CAS 1544673-40-6
| CAS No. | 1544673-40-6 |
| Molecular Formula | C13H18BClO3 |
| Molecular Weight | 268.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 268.54 g/mol gives (4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol (CAS 1544673-40-6) is a high-purity analytical reference standard with the molecular formula C13H18BClO3 and a molecular weight of 268.54 g/mol.
The molecular framework of (4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol (C13H18BClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18BClO3 |
| Molecular Weight | 268.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 3-Chloro-4-(hydroxymethyl)phenylboronic Acid Pinacol Ester (CAS 1051316-34-7)
- 2-(2-Chloro-6-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1061367-22-3)
- 3-Chloro-5-(hydroxymethyl)phenylboronic Acid Pinacol Ester (CAS 1112210-59-9)
- 2-Chloro-3-methoxyphenylboronic Acid Pinacol Ester (CAS 1151564-03-2)
- 2-(3-Chloro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1165936-01-5)
- 2-(2-Chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1256781-73-3)
- 2-Chloro-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 1294518-25-4)
- 2-Chloro-3-(hydroxymethyl)phenylboronic Acid Pinacol Ester (CAS 1400755-07-8)
Recommended Standards
- 2-Chloro-4-(hydroxymethyl)phenylboronic Acid Pinacol Ester (CAS 1485110-17-5)
- 3-Bromo-4-phenyl-2-chloropyridine (CAS 1622838-93-0)
- 3-Bromo-5-chloro-2-phenylpyridine (CAS 1469759-15-6)
- 2-(3-Chloro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628502-45-3)
- 2-3-5-Tri-O-benzyl-D-arabino-1-4-lactone (CAS 14233-64-8)
- 3,5-Dibromo-4-methylpyridin-2(1H)-one (CAS 89581-53-3)
- Ethyl 5-(4-biphenyl)-5-oxovalerate (CAS 138247-17-3)
- 2-Phenethoxybenzaldehyde (CAS 93898-91-0)
- 21554-74-5 (2-Methoxyphenyl)(3-methoxyphenyl)methanone DTXSID30493204 (CAS 21554-74-5)
- Avanafil Impurity 47 (CAS CATO-C4X-111847)
- Thiotolyl β-D-ribofuranoside (CAS 1131610-84-8)
- 4-Tert-Butylphenethyl Alcohol (CAS 5406-86-0)
- 3-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole (CAS 374715-22-7)
- Tau Peptide (379-408) trifluoroacetate salt (CAS 1246357-53-8)
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