3-Fluorothiophene-2-carbonitrile CAS 154499-46-4
| CAS No. | 154499-46-4 |
| Molecular Formula | C5H2FNS |
| Molecular Weight | 127.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 127.14 g/mol gives 3-Fluorothiophene-2-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Fluorothiophene-2-carbonitrile (CAS 154499-46-4), molecular formula C5H2FNS and molecular weight 127.14 g/mol, is a CATO reference standard with documented purity and traceability.
3-Fluorothiophene-2-carbonitrile (C5H2FNS) contains a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Fluorothiophene-2-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H2FNS |
| Molecular Weight | 127.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluorothiophene Standards
- 4-Fluorothiophene-2-carbonitrile (CAS 32431-77-9)
- 5-Fluorothiophene-3-carbonitrile (CAS 32415-55-7)
- 2-Fluorothiophene-3-carbaldehyde (CAS 614729-71-4)
- 4-Fluorothiophene-3-carbaldehyde (CAS 614729-75-8)
- 5-fluorothiophene-2-carbonitrile (CAS 32415-91-1)
- 5-Fluorothiophene-2-methanamine (CAS 214759-36-1)
- 3-fluorothiophene-2-carbaldehyde (CAS 32431-83-7)
- 4-fluorothiophene-2-carbaldehyde (CAS 32431-71-3)
Recommended Standards
- 2-Azabicyclo[2.1.1]Hexane-3-carboxylic acid (CAS 1544365-08-3)
- (1R,2S)-2-Aminocyclopent-3-ene-1-carboxylic acid (CAS 154568-20-4)
- 3-(Hydroxymethyl)tetrahydrofuran-3-carbonitrile (CAS 1537271-57-0)
- 2-Amino-5,5-dimethyl-3,5-dihydro-4H-imidazol-4-one (CAS 1546616-89-0)
- 4-Ethoxy-N-(pyridin-4-ylmethyl)aniline (CAS 16552-50-4)
- (S)-(5-Bromo-6-(1-methoxyethyl)pyridin-3-yl)boronic acid (CAS 2641451-77-4)
- 2-Fluoro-N-(1-(thiazol-2-yl)ethyl)aniline (CAS 1465087-69-7)
- (R)-2-Chloro-1-(3-pyridyl)ethanol (CAS 173901-03-6)
- SU5408 (CAS 15966-93-5)
- 4-Chloro-2-(4-fluorophenyl)-6-nitroquinoline (CAS 1416440-17-9)
- 3-Isopropyl-1,5-dimethyl-3,7-diaza-bicyclo[3.3.1]-nonan-9-ol (CAS 956938-47-9)
- (3-Aminophenyl)(4-methylpiperidin-1-yl)methanone (CAS 915908-51-9)
- 2,2′-Methylenebis[(4<I>S</I>)-4-tert-butyl-2-oxazoline] (CAS 132098-54-5)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
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