1-Chloro-N-[2-(ethylsulfonyl)-5-(trifluoromethyl)phenyl]methanesulfonamide CAS 1546-17-4
| CAS No. | 1546-17-4 |
| Molecular Formula | C10H11ClF3NO4S2 |
| Molecular Weight | 365.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Chloro-N-[2-(ethylsulfonyl)-5-(trifluoromethyl)phenyl]methanesulfonamide.
1-Chloro-N-[2-(ethylsulfonyl)-5-(trifluoromethyl)phenyl]methanesulfonamide (CAS 1546-17-4) is a high-purity analytical reference standard with the molecular formula C10H11ClF3NO4S2 and a molecular weight of 365.78 g/mol.
1-Chloro-N-[2-(ethylsulfonyl)-5-(trifluoromethyl)phenyl]methanesulfonamide (C10H11ClF3NO4S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Chloro-N-[2-(ethylsulfonyl)-5-(trifluoromethyl)phenyl]methanesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11ClF3NO4S2 |
| Molecular Weight | 365.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chloro Standards
- Ethyl 3-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanoate (CAS 1672655-81-0)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-hydroxyethyl)-N-methylpiperidine-4-carboxamide (CAS 303150-26-7)
- 2-(5-Chloro-2,4-dimethoxyphenyl)-1-oxo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic acid (CAS 1005262-38-3)
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Recommended Standards
- Tert-butyl (1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)carbamate (CAS 1354448-68-2)
- Tert-butyl 4-(6-chloro-4-(trifluoromethyl)pyridin-2-yl)piperazine-1-carboxylate (CAS 1201675-03-7)
- (2E)-N-(3-Chloro-4-fluorophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-enamide (CAS 329778-84-9)
- 1-tert-Butyloxycarbonyl-4-(3-Chloro-5-(trifluoro-methyl)pyridin-2-yl)piperazine (CAS 1053658-78-8)
- 2-((2,5-Dimethyl-1h-pyrrol-3-yl)methylene)malononitrile (CAS 326866-77-7)
- (1R,2R)-1-iodo-2-(perfluoropropyl)cyclohexane (CAS 7589-43-7)
- 4-Iodo-1-(2,2,2-trifluoroethyl)-1H-pyrazole (CAS 918483-35-9)
- 2-[2-(trifluoromethyl)-1,3-thiazol-4-yl]acetic acid (CAS 1082267-60-4)
- 2-Amino-3-(3-chloro-4-methoxyphenyl)propanoic acid (CAS 603105-74-4)
- 4-Bromo-2-(carboxycarbonyl)-6-chlorobenzoic acid (CAS 2629317-64-0)
- 4-(4-Methyl-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 577698-43-2)
- 2,2'-Dibromo-6-chloro-1,1'-biphenyl (CAS 1300117-83-2)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-methoxypyridin-4-amine (CAS 1806889-87-1)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
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