8-Chloro-1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid CAS 99696-22-7
| CAS No. | 99696-22-7 |
| Molecular Formula | C17H17ClFN3O3 |
| Molecular Weight | 365.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 365.79 g/mol gives 8-Chloro-1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Chloro-1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 99696-22-7), molecular formula C17H17ClFN3O3 and molecular weight 365.79 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 8-Chloro-1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (C17H17ClFN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 365.79 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Chloro-1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17ClFN3O3 |
| Molecular Weight | 365.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Ethyl 4-chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS 1987286-78-1)
- N-(3-chloro-4-fluorophenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide (CAS 329080-46-8)
- N-(3-chloro-4-fluorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 329079-97-2)
- N-(3-chloro-5-fluorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 882082-07-7)
- 1-Chloro-N-[2-(ethylsulfonyl)-5-(trifluoromethyl)phenyl]methanesulfonamide (CAS 1546-17-4)
- Ethyl 3-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanoate (CAS 1672655-81-0)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-hydroxyethyl)-N-methylpiperidine-4-carboxamide (CAS 303150-26-7)
- 3-(N-(4-chloro-3-methylisoxazol-5-yl)sulfamoyl)-N-methoxy-N-methylthiophene-2-carboxamide (CAS 210421-71-9)
Recommended Standards
- 3-(4-Fluorophenyl)-1H-pyrazole-4-carbaldehyde N-(7-chloro-4-quinolinyl)hydrazone (CAS 477711-39-0)
- 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,2-dihydro-3H-pyrazol-3-one (CAS 219138-24-6)
- N-(3-(4-chlorophenyl)imidazo[1,2-a]pyridin-8-yl)-2-fluorobenzamide (CAS 439096-62-5)
- 1-(4-Methylbenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-sulfonyl chloride (CAS 1334147-61-3)
- 3-Cyano-3-(4-methoxyphenyl)propanoic acid (CAS 32856-74-9)
- 4-Bromo-N1-phenylbenzene-1,2-diamine (CAS 68765-53-7)
- 2-Amino-5-phenyl-1,3-thiazole-4-carbohydrazide (CAS 709639-25-8)
- 2,6-Bis[(4S)-4-(1,1-dimethylethyl)-4,5-dihydro-2-oxazolyl]-4-methoxypyridine (CAS 825613-47-6)
- 2-(2-(4-Chlorophenyl)-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-2-cyclohexylethan-1-ol (CAS 1335213-32-5)
- Naphtho[1,2-d]thiazole-2-carbonitrile (CAS 39785-46-1)
- rac 7-Hydroxy Propranolol (CAS 81907-81-5)
- (5-Methyl-3H-imidazo[4,5-b]pyridin-2-yl)methanamine (CAS 220658-95-7)
- methyl 4-(2-chlorophenyl)-5-cyano-2-oxo-6-sulfanyl-3,4-dihydro-1H-pyridine-3-carboxylate;4-methylmorpholine (CAS 1078161-58-6)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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