Methyl 2-(trifluoromethyl)piperidine-4-carboxylate CAS 1546798-16-6
| CAS No. | 1546798-16-6 |
| Molecular Formula | C8H12F3NO2 |
| Molecular Weight | 211.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Methyl 2-(trifluoromethyl)piperidine-4-carboxylate (CAS 1546798-16-6), a certified reference material (molecular formula C8H12F3NO2, MW 211.18 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Methyl 2-(trifluoromethyl)piperidine-4-carboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H12F3NO2 |
| Molecular Weight | 211.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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- 2-[4-(Trifluoromethyl)phenyl]pyrrole (CAS 115464-88-5)
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- Ethyl 3-(trifluoromethyl)pyrrolidine-3-carboxylate (CAS 1211537-93-7)
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Recommended Standards
- 1-(1H-1,2,3,4-Tetrazole-5-carbonyl)pyrrolidine-3-carboxylic acid (CAS 1515756-30-5)
- 2,2,2-Trifluoro-1-(4-(hydroxymethyl)piperidin-1-yl)ethan-1-one (CAS 156459-82-4)
- 2-(1-(2,2,2-Trifluoroethyl)pyrrolidin-3-yl)acetic acid (CAS 1508620-50-5)
- 1-(Trifluoromethyl)naphthalen-2-amine (CAS 161431-58-9)
- 3-(Dimethylphosphoryl)benzonitrile (CAS 1333230-29-7)
- N-methyl-N-(4-(morpholinosulfonyl)-2-nitrophenyl)glycine (CAS 866145-94-0)
- Dimethyl 2,3-dicyanomaleate (CAS 101342-44-3)
- Ethyl 2-acetamidobenzo[b]thiophene-3-carboxylate (CAS 7311-77-5)
- Ethyl 4-hydroxyphthalazine-1-carboxylate (CAS 23952-05-8)
- Fasudil Impurity 43 (CAS 84468-24-6)
- 1-(2-(Bromomethyl)phenyl)-1h-1,2,4-triazole (CAS 1138399-31-1)
- 1-{4-[(2-ethylhexyl)oxy]phenyl}ethan-1-one (CAS 132944-37-7)
- 1-(2-(Aminomethyl)pyrrolidin-1-yl)ethan-1-one (CAS 62105-09-3)
- Calcineurin Autoinhibitory Peptide (CAS 148067-21-4)
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