Ethyl 2,4-dichloro-7-fluoroquinoline-3-carboxylate CAS 1546989-15-4
| CAS No. | 1546989-15-4 |
| Molecular Formula | C12H8Cl2FNO2 |
| Molecular Weight | 288.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2,4-dichloro-7-fluoroquinoline-3-carboxylate.
CATO supplies Ethyl 2,4-dichloro-7-fluoroquinoline-3-carboxylate (CAS 1546989-15-4), a certified reference material (molecular formula C12H8Cl2FNO2, MW 288.10 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Ethyl 2,4-dichloro-7-fluoroquinoline-3-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 288.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 2,4-dichloro-7-fluoroquinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl2FNO2 |
| Molecular Weight | 288.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 4,6-dichloro-8-fluoroquinoline-3-carboxylate (CAS 338795-17-8)
- Ethyl 4,7-dichloro-6-fluoroquinoline-3-carboxylate (CAS 218457-57-9)
- (S)-2-(5,6-Dichloro-1,3-dioxoisoindolin-2-yl)propanoic acid (CAS 111104-26-8)
- 2-(5,6-Dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid (CAS 111187-17-8)
- 2-((4,5-Dichloro-1H-imidazol-1-yl)methyl)-3,4-dimethoxypyridine (CAS 1219570-73-6)
- 1-(2,4-DIchloro-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester (CAS 1239769-46-0)
- 5-((2,4-Dichloro-3,5-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-amine (CAS 1706445-66-0)
- 5-((4,6-Dichloro-2,3-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-amine (CAS 1706455-70-0)
Recommended Standards
- tert-Butyl(dibromomethyl)dimethylsilane (CAS 148259-35-2)
- 3-(6-Amino-8-bromo-3H-purin-3-yl)-2-oxopropanal (CAS 169776-86-7)
- 3-Iodobenzo[b]thiophene-2-carbaldehyde (CAS 1259895-71-0)
- 1-Fluoro-3-(4-iodophenyl)bicyclo[1.1.1]Pentane (CAS 1934526-34-7)
- (4-(Piperidin-4-yl)phenyl)methanol (CAS 885274-59-9)
- 2-(Chloromethyl)-5-(thiophen-2-yl)-3H,4H-thieno[2,3-d]pyrimidin-4-one (CAS 255378-83-7)
- Stavudine sodium (CAS 134624-73-0)
- (±)-3-Amino-1,2-propanediol (CAS 616-30-8)
- n-(2-(Isopentyloxy)ethyl)thieno[3,2-d]pyrimidin-4-amine (CAS 1306474-82-7)
- 2-(1,3-Dioxooctahydro-4,6-ethenocyclopropa-[f]isoindol-2(1H)-yl)-3-methylbutanoic acid (CAS 436811-19-7)
- 3-(4-Bromophenyl)benzo[c]isoxazole (CAS 1140-36-9)
- 5-(azidomethyl)oxolan-2-one (CAS 24211-53-8)
- 2-Bromo-5-((tert-butoxycarbonyl)amino)-4-methylbenzoic acid (CAS 1881987-02-5)
- Semaglutide impurity 01 (CAS 1998701-31-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com