Ethyl 4,6-dichloro-8-fluoroquinoline-3-carboxylate CAS 338795-17-8
| CAS No. | 338795-17-8 |
| Molecular Formula | C12H8Cl2FNO2 |
| Molecular Weight | 288.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Ethyl 4,6-dichloro-8-fluoroquinoline-3-carboxylate (CAS 338795-17-8), a certified reference material (molecular formula C12H8Cl2FNO2, MW 288.10 g/mol) for analytical method development and quality control.
Ethyl 4,6-dichloro-8-fluoroquinoline-3-carboxylate (C12H8Cl2FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Ethyl 4,6-dichloro-8-fluoroquinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl2FNO2 |
| Molecular Weight | 288.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 2,4-dichloro-7-fluoroquinoline-3-carboxylate (CAS 1546989-15-4)
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