4-[(7-Chloroquinolin-4-ylAmino]-2-(Diethylaminomethyl)-3,6-Difluorophenol CAS 155020-40-9
| CAS No. | 155020-40-9 |
| Molecular Formula | C20H20ClF2N3O |
| Molecular Weight | 391.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-[(7-Chloroquinolin-4-ylAmino]-2-(Diethylaminomethyl)-3,6-Difluorophenol (C20H20ClF2N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-[(7-Chloroquinolin-4-ylAmino]-2-(Diethylaminomethyl)-3,6-Difluorophenol (CAS 155020-40-9) is a high-purity analytical reference standard with the molecular formula C20H20ClF2N3O and a molecular weight of 391.84 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-[(7-Chloroquinolin-4-ylAmino]-2-(Diethylaminomethyl)-3,6-Difluorophenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H20ClF2N3O |
| Molecular Weight | 391.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloroquinolin Standards
- 12-((5-Chloroquinolin-8-yl)oxy)dodecyl acetate (CAS 88350-02-1)
- 1,4-Bis(7-chloroquinolin-4-yl)piperazine (CAS 31502-87-1)
- 1-(7-Chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylic acid (CAS 1146757-92-7)
- 4-(1-((7-Chloroquinolin-4-yl)amino)-4-(diethylamino)butan-2-yl)phenol (CAS 5431-70-9)
- 2-[(5-Chloroquinolin-8-yl)oxy]-N-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)acetamide (CAS 874611-72-0)
- 5-Chloroquinolin-8-yl (2,5-dichlorophenyl)carbamate (CAS 21617-09-4)
- 5-Chloroquinolin-8-yl (3,4-dichlorophenyl)carbamate (CAS 21617-26-5)
- 5-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenol (CAS 1643-45-4)
Recommended Standards
- 2-(4-Chlorophenoxy)-N,2-dimethyl-N-(2,3,4,5,6-pentahydroxyhexyl)propanamide (CAS 1038922-14-3)
- 1,2-Bis(bromodifluoromethoxy)-1,1,2,2-tetrafluoroethane (CAS 330562-48-6)
- Trelagliptin impurity 92 (CAS CATO-C4X-104692)
- 4-[(E)-2-(2-Chlorophenyl)ethenyl]-6-(trifluoromethyl)-2H,3H-thieno[3,2-c]quinoline (CAS 865658-33-9)
- 4-Chloro-6-methylpicolinic acid hydrochloride (CAS 1841081-42-2)
- m-Tolylmagnesium chloride (CAS 121905-60-0)
- 4-(1H-Pyrrol-1-yl)-N-(thiophen-3-ylmethyl)benzamide (CAS 1286726-82-6)
- cis-3-Methyl-cyclohexanecarboxylic acid (CAS 73873-48-0)
- (R)-3-Methyl-5-(piperidin-2-yl)isoxazole (CAS 164351-53-5)
- 4-[(2-fluorophenyl)methyl]-3-methylmorpholine (CAS 1252499-28-7)
- N-((R)-1-((S)-2-Amino-3-methylbutanoyl)pyrrolidin-3-yl)-N-cyclopropylacetamide (CAS 1401665-85-7)
- H-Ala(3-(N,N-Diethylamino))-OH (CAS 754167-24-3)
- 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-(2,4-difluorobenzyl)piperidine-4-carboxylic acid (CAS 916422-05-4)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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