(1-(3-Chloro-2-fluorophenyl)cyclobutyl)methanamine CAS 1551124-62-9
| CAS No. | 1551124-62-9 |
| Molecular Formula | C11H13ClFN |
| Molecular Weight | 213.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(1-(3-Chloro-2-fluorophenyl)cyclobutyl)methanamine (CAS 1551124-62-9) is a high-purity analytical reference standard with the molecular formula C11H13ClFN and a molecular weight of 213.68 g/mol.
The molecular framework of (1-(3-Chloro-2-fluorophenyl)cyclobutyl)methanamine (C11H13ClFN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (1-(3-Chloro-2-fluorophenyl)cyclobutyl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13ClFN |
| Molecular Weight | 213.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 1-(3-Chloro-2-fluorophenyl)cyclopentanamine (CAS 1546214-97-4)
- 1-(4-Chloro-3-fluorophenyl)cyclopentanamine (CAS 1704112-83-3)
- (1-(4-Chloro-3-fluorophenyl)cyclobutyl)methanamine (CAS 1541027-06-8)
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- 2-iodo-1H-pyrrolo[2,3-b]pyridine (CAS 1227270-32-7)
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- 2-((8-Hydroxyquinolin-5-yl)methyl)isoindoline-1,3-dione (CAS 72201-23-1)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
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