Flupirtine Impurity 5 CAS 1552323-75-7
| CAS No. | 1552323-75-7 |
| Molecular Formula | C18H21FN4O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 412.85 g/mol gives Flupirtine Impurity 5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Flupirtine Impurity 5 (CAS 1552323-75-7, C18H21FN4O4HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Flupirtine Impurity 5 (C18H21FN4O4HCl) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H21FN4O4 HCl |
| Molecular Weight | 412.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Flupirtine Standards
- Flupirtine-N6-β-D-Glucuronide (CAS 1147289-72-2)
- Flupirtine-N2-β-D-Glucuronide (CAS 1147289-74-4)
- Flupirtine-D4 Hydrochloride (CAS 1324717-75-0)
- Flupirtine Impurity 8 (CAS 140-75-0)
- Flupirtine Impurity 1 (CAS 1417916-52-9)
- Flupirtine Impurity 4 (CAS 1506942-35-3)
- Flupirtine Impurity H (CAS 16013-85-7)
- Flupirtine Impurity C (CAS 21626-43-7)
Recommended Standards
- 7-TMCA Impurity 2 (CAS 126437-69-2)
- Imipenem Impurity 12 (CAS CATO-C4X-166212)
- Rosuvastatin Impurity 119 (CAS CATO-C4X-1169119)
- 4-Amino-N,3-dimethylbenzamide hydrochloride (CAS 1269394-46-8)
- Md2-in-1 (CAS 111797-22-9)
- 1-(1-(4-Methoxyphenyl)-5-methyl-1H-pyrazol-4-yl)ethan-1-one (CAS 96723-55-6)
- 3,5-Dibromo-2-methoxypyridine (CAS 13472-60-1)
- (1R,4aR,4bR,10aR)-Ethyl 7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydrophenanthrene-1-carboxylate (CAS 631-71-0)
- 6-Chloro-N'-hydroxypicolinimidamide (CAS 1042151-12-1)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com