Minoxidil EP Impurity B CAS 156-83-2

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.156-83-2
Molecular FormulaC4H5ClN4
Molecular Weight144.56 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Minoxidil EP Impurity B CAS 156-83-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Minoxidil EP Impurity B.

Minoxidil EP Impurity B (CAS 156-83-2) is a certified pharmaceutical impurity reference standard with the molecular formula C4H5ClN4 and a molecular weight of 144.56 g/mol.

Structurally, Minoxidil EP Impurity B (C4H5ClN4) contains a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 144.56 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Minoxidil EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H5ClN4
Molecular Weight144.56 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1957
Halogen ContentCl-containing
Nitrogen Atoms4

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