4-(4-Chlorobenzylidene)-2-phenyloxazol-5(4H)-one CAS 15601-44-2
| CAS No. | 15601-44-2 |
| Molecular Formula | C16H10ClNO2 |
| Molecular Weight | 283.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(4-Chlorobenzylidene)-2-phenyloxazol-5(4H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(4-Chlorobenzylidene)-2-phenyloxazol-5(4H)-one (CAS 15601-44-2), molecular formula C16H10ClNO2 and molecular weight 283.71 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(4-Chlorobenzylidene)-2-phenyloxazol-5(4H)-one (C16H10ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 283.71 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10ClNO2 |
| Molecular Weight | 283.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzylidene Standards
- (Z)-4-(2-chlorobenzylidene)-2-phenyloxazol-5(4h)-one (CAS 77435-90-6)
- (Z)-4-(4-chlorobenzylidene)-2-phenyloxazol-5(4h)-one (CAS 57427-77-7)
- 3-((2-Chlorobenzylidene)hydrazono)indolin-2-one (CAS 86710-18-1)
- 3-((3-Chlorobenzylidene)amino)quinazolin-4(3H)-one (CAS 95446-32-5)
- 3-((4-Chlorobenzylidene)amino)quinazolin-4(3H)-one (CAS 88404-48-2)
- 3-((4-Chlorobenzylidene)hydrazono)indolin-2-one (CAS 70565-02-5)
- 3-(4-Chlorobenzylidene)-5-phenylfuran-2(3H)-one (CAS 13294-94-5)
- 2-(4-Chlorobenzylidene)-6-hydroxy-4-methylbenzofuran-3(2H)-one (CAS 903868-79-1)
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