4-Benzyloxy-2-(trifluoromethoxy)phenylboronic acid CAS 1562343-86-5
| CAS No. | 1562343-86-5 |
| Molecular Formula | C14H12BF3O4 |
| Molecular Weight | 312.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Benzyloxy-2-(trifluoromethoxy)phenylboronic acid (CAS 1562343-86-5), a certified reference material (molecular formula C14H12BF3O4, MW 312.05 g/mol) for analytical method development and quality control.
Structurally, 4-Benzyloxy-2-(trifluoromethoxy)phenylboronic acid (C14H12BF3O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 312.05 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12BF3O4 |
| Molecular Weight | 312.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related Benzyloxy Standards
- (3-(Benzyloxy)-5-(trifluoromethoxy)phenyl)boronic acid (CAS 1256345-95-5)
- 2-Benzyloxy-4-(trifluoromethoxy)phenylboronic acid (CAS 1704064-19-6)
- 4-(Benzyloxy)-2-iodopyrimidine (CAS 1333319-56-4)
- 2-(Benzyloxy)-4-iodopyrimidine (CAS 1333319-69-9)
- 2-(Benzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 1218791-34-4)
- 2-(Benzyloxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine (CAS 2077892-11-4)
- 4-Benzyloxy-2-(trifluoromethoxy)benzoic acid (CAS 1809161-55-4)
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Recommended Standards
- Ethyl 2,4-difluoro-5-iodobenzoate (CAS 1541937-20-5)
- Ethyl 2,6-difluoro-3-iodobenzoate (CAS 1520299-34-6)
- 4-Chloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoropyrimidine (CAS 1823188-18-6)
- Methyl 4-(difluoromethyl)-3-iodobenzoate (CAS 1488423-65-9)
- Benzyl (2-((1,3-dioxoisoindolin-2-yl)oxy)ethyl)carbamate (CAS 168827-96-1)
- (1r)-1-(4-Bromothiophen-2-yl)-2,2,2-trifluoroethan-1-ol (CAS 1423015-71-7)
- 5-chloro-1-methyl-pyrazolo[3,4-c]pyridine (CAS 1521237-92-2)
- 2-Bromo-5-chloro-3-methoxybenzonitrile (CAS 1891745-13-3)
- 1-Amino-1-cyclopropyl-2-methylpropan-2-ol (CAS 1537355-17-1)
- 17-Ethinyl-17-hydroxy-18-methylestra-5(10),9(11)-dien-3-one-3-ethylene ketal 23637-79-8 3-Iodo-1H-pyrrolo[2,3-b]pyridine (CAS 23637-79-8)
- 4-Amino-N-isobutyl-1-methyl-1h-pyrazole-5-carboxamide (CAS 1001500-37-3)
- (5-Amino-2-iodophenyl)methanol (CAS 1261609-99-7)
- 7-Bromo-1-methyl-1H-benzo[d]imidazole-5-carboxylic acid (CAS 1378260-24-2)
- Cyclolinopeptide B (CAS 193139-41-2)
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