Dapoxetine Impurity 19 CAS 156453-53-1
| CAS No. | 156453-53-1 |
| Molecular Formula | C19H18O2 |
| Molecular Weight | 278.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Dapoxetine Impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Dapoxetine Impurity 19 (CAS 156453-53-1, C19H18O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dapoxetine Impurity 19 (C19H18O2) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 278.35 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H18O2 |
| Molecular Weight | 278.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
Related Dapoxetine Standards
- Dapoxetine Impurity 10 (CAS 908291-72-5)
- Dapoxetine Impurity 20 (CAS 156453-50-8)
- Dapoxetine Impurity 89 (CAS CATO-C4X-143989)
- Dapoxetine Impurity 4 (CAS 119357-34-5)
- Dapoxetine Impurity 5 (CAS 1329834-62-9)
- Dapoxetine Impurity 6 (CAS 147199-40-4)
- Dapoxetine Impurity 17 (CAS 41198-42-9)
- Dapoxetine Impurity 57 (CAS 126113-24-4)
Recommended Standards
- N,O-Didesmethyl-N-Nitroso Venlafaxine (CAS 3017268-48-0)
- Avibactam Impurity 9 (CAS 2085372-13-8)
- N-Desmethyl N-Nitroso Tramadol (Mixture of Enantiomers) (CAS CATO-C4X-149814)
- Avibactam Impurity 78 (CAS CATO-C4X-134878)
- Lapatinib Impurity 46 (CAS 320337-10-8)
- Sildenafil Impurity 55 (CAS 92945-27-2)
- Brivudine Impurity N2 (CAS 69304-49-0)
- (R)-2-Amino-4-(2,6-difluorophenyl)butanoic acid (CAS 1260596-10-8)
- 4,5-Dimethoxy-1H-indole-3-carbaldehyde (CAS 154810-58-9)
- 2-Ethylcyclohexane-1-carbaldehyde (CAS 1222900-26-6)
- trans-3-Phenylcyclobutanamine (CAS 1570-99-6)
- Sodium 2-(dicyclohexylphosphino)-2',6'-dimethoxybiphenyl-3'-sulfonate (CAS 870245-75-3)
- Methyl 4-sulfamoylbenzoate (CAS 22808-73-7)
- Cyclopeptide-5 (CAS 197172-76-2)
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