| CAS No. | 15686-33-6 |
| Molecular Formula | C21H26Cl2O2 |
| Molecular Weight | 381.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 381.34 g/mol gives 6,6'-Methylenebis(4-chloro-2-isopropyl-5-methylphenol) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6,6'-Methylenebis(4-chloro-2-isopropyl-5-methylphenol) (CAS 15686-33-6), molecular formula C21H26Cl2O2 and molecular weight 381.34 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, a hydroxyl group, an ether linkage, chlorine substitution, 6,6'-Methylenebis(4-chloro-2-isopropyl-5-methylphenol) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 381.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6,6'-Methylenebis(4-chloro-2-isopropyl-5-methylphenol) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C21H26Cl2O2 |
| Molecular Weight | 381.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |