2,2＇-Methylenebis(6-cyclohexyl-p-cresol) CAS 4066-02-8
| CAS No. | 4066-02-8 |
| Molecular Formula | C27H36O2 |
| Molecular Weight | 392.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,2＇-Methylenebis(6-cyclohexyl-p-cresol) (CAS 4066-02-8), molecular formula C27H36O2 and molecular weight 392.57 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, a hydroxyl group, an ether linkage, 2,2＇-Methylenebis(6-cyclohexyl-p-cresol) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 392.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H36O2 |
| Molecular Weight | 392.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Methylenebis Standards
- 3,3'-((Methylenebis(oxy))bis(4,1-phenylene))bis(pyrrolidine-2,5-dione) (CAS 87367-86-0)
- 5,5-Methylenebis(4-benzyl-4H-1,2,4-triazole-3-thiol) (CAS 62575-53-5)
- 1,1'-(Methylenebis(4,1-phenylene))bis(3-butylurea) (CAS 77703-56-1)
- 4,4′-[Methylenebis(4,1-phenyleneimino)]bis[4-oxobutanoic acid] (CAS 155267-38-2)
- 6,6'-Methylenebis(4-chloro-2-isopropyl-5-methylphenol) (CAS 15686-33-6)
- 4,4＇-Methylenebis(3-chloro-2,6-diethylaniline) (CAS 106246-33-7)
- 2,2′-[Methylenebis(4,1-phenylenenitrilomethylidyne)]bis[phenol] (CAS 4434-23-5)
- 1,1'-(Methylenebis(2,4-dihydroxy-6-methoxy-3,1-phenylene))bis(ethan-1-one) (CAS 142382-28-3)
Recommended Standards
- Deoxycholic acid impurity 32 (CAS CATO-C4X-335932)
- 5beta-Cholanic Acid-3alpha,6beta-diol (CAS 668-49-5)
- Deoxycholic acid Impurity 14 (CAS 1334203-40-5)
- Hyodeoxycholic Acid (CAS 83-49-8)
- 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-10,11-dihydro-6'-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione (CAS 1204591-53-6)
- N-Methoxy-N-methyl-2-(thiophen-2-yl)acetamide (CAS 125067-45-0)
- 3,4-Difluoro-3-thiomorpholinomethyl benzophenone (CAS 898787-96-7)
- 2,4,5-Trifluoro-3-methoxy-6-methylbenzonitrile (CAS 1003708-50-6)
- Roxadustat Impurity 25 (CAS 2699139-12-1)
- 1-(2,6-Dimethylphenyl)ethan-1-amine (CAS 1270484-28-0)
- 1-Bromo-1,1-dichlorotrifluoroethane (CAS 354-50-7)
- 1-Methyl-3-(thiophen-2-yl)-1h-pyrazole-4-carboxylic acid (CAS 1152510-37-6)
- 5-Acetyl-2-pyrrolidinone (CAS 85858-09-9)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
Why CATO?
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