8-Bromo-2',3',5'-tri-O-acetylguanosine CAS 15717-45-0

Purity 97%+In StockPharmaceutical Standards
CAS No.15717-45-0
Molecular FormulaC16H18BrN5O8
Molecular Weight488.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-Bromo-2',3',5'-tri-O-acetylguanosine CAS 15717-45-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Bromo-2',3',5'-tri-O-acetylguanosine.

8-Bromo-2',3',5'-tri-O-acetylguanosine (CAS 15717-45-0) is a high-purity analytical reference standard with the molecular formula C16H18BrN5O8 and a molecular weight of 488.25 g/mol.

The molecular framework of 8-Bromo-2',3',5'-tri-O-acetylguanosine (C16H18BrN5O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 8-Bromo-2',3',5'-tri-O-acetylguanosine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H18BrN5O8
Molecular Weight488.25 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Halogen ContentBr-containing
Nitrogen Atoms5

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