4-chloroquinoline-3-sulfonyl chloride CAS 157494-40-1
| CAS No. | 157494-40-1 |
| Molecular Formula | C9H5Cl2NO2S |
| Molecular Weight | 262.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-chloroquinoline-3-sulfonyl chloride (C9H5Cl2NO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-chloroquinoline-3-sulfonyl chloride (CAS 157494-40-1) is a high-purity analytical reference standard with the molecular formula C9H5Cl2NO2S and a molecular weight of 262.11 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-chloroquinoline-3-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5Cl2NO2S |
| Molecular Weight | 262.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related chloroquinoline Standards
- 7-Chloroquinoline-4-sulfonyl chloride (CAS 1134937-73-7)
- 6-Chloroquinoline-2-sulfonyl chloride (CAS 1219101-08-2)
- 6-Chloroquinoline-4-sulfonyl chloride (CAS 1219101-09-3)
- 6-Chloroquinoline-3-sulfonyl chloride (CAS 1360625-43-9)
- 2-Chloroquinoline-6-sulfonyl Chloride (CAS 205055-71-6)
- 4-chloroquinoline-8-sulfonyl chloride (CAS 66533-26-4)
- 8-CHLOROQUINOLINE-3-SULFONYL CHLORIDE (CAS 847727-25-7)
- 8-Chloroquinoline-5-sulfonyl chloride (CAS 930396-13-7)
Recommended Standards
- 2-(5-(4-Bromophenyl)-1H-pyrazol-3-yl)acetonitrile (CAS 153391-40-3)
- 2-Bromo-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine (CAS 1802412-74-3)
- 4-Amino-8-bromo-7-methylquinoline-3-carbonitrile (CAS 1513808-82-6)
- 4-Chloroisoquinoline-5-sulfonyl chloride (CAS 194032-34-3)
- 229956-97-2 4,4,4-Trifluoro-3,3-dimethoxybutanol MFCD00673742 (CAS 229956-97-2)
- 2-Chloro-5-methoxyquinoxaline (CAS 76052-76-1)
- (S)-2-(2-bromo-3-methylphenyl)pyrrolidine (CAS 1213619-31-8)
- 1,2-Bis((1,3-dioxolan-2-yl)oxy)ethane (CAS 4544-19-8)
- Methyl 8-methyl-2-phenyl-[1,2,4]triazolo[1,5-a]pyridine-7-carboxylate (CAS 1380331-21-4)
- 1-(2-Bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-2,2-dimethylpropan-1-one (CAS 1184852-23-0)
- Ethyl 5-aminoindoline-1-carboxylate (CAS 1021106-45-5)
- 3-hydroxypropionaldehyde (CAS 2134-29-4)
- (2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl)-acetic acid (CAS 247228-33-7)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com