4-chloroquinoline-8-sulfonyl chloride CAS 66533-26-4
| CAS No. | 66533-26-4 |
| Molecular Formula | C9H5Cl2NO2S |
| Molecular Weight | 262.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C9H5Cl2NO2S, 4-chloroquinoline-8-sulfonyl chloride contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 262.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-chloroquinoline-8-sulfonyl chloride (CAS 66533-26-4), a certified reference material (molecular formula C9H5Cl2NO2S, MW 262.11 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5Cl2NO2S |
| Molecular Weight | 262.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related chloroquinoline Standards
- 7-Chloroquinoline-4-sulfonyl chloride (CAS 1134937-73-7)
- 6-Chloroquinoline-2-sulfonyl chloride (CAS 1219101-08-2)
- 6-Chloroquinoline-4-sulfonyl chloride (CAS 1219101-09-3)
- 6-Chloroquinoline-3-sulfonyl chloride (CAS 1360625-43-9)
- 4-chloroquinoline-3-sulfonyl chloride (CAS 157494-40-1)
- 2-Chloroquinoline-6-sulfonyl Chloride (CAS 205055-71-6)
- 8-CHLOROQUINOLINE-3-SULFONYL CHLORIDE (CAS 847727-25-7)
- 8-Chloroquinoline-5-sulfonyl chloride (CAS 930396-13-7)
Recommended Standards
- 4-Bromo-2-(1H-pyrazol-3-yl)-1H-indole (CAS 827317-27-1)
- 4-Methoxy-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (CAS 443776-90-7)
- 4-Acetoxyphenylboronic Acid Pinacol Ester (CAS 480424-70-2)
- 4-Methyl-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid (CAS 2377608-70-1)
- Brevetoxin A (CAS 98112-41-5)
- 3-Methyl-2,5-bis(trifluoromethyl)benzamide (CAS 1806050-64-5)
- Ethyl 3-(3-hydroxyphenyl)-1H-1,2,4-triazole-5-carboxylate (CAS 1416343-18-4)
- 3-Fluoro-5-(trifluoromethoxy)pyridin-2-amine (CAS 1092351-62-6)
- 6-Bromofuro[2,3-d]pyrimidin-4-amine (CAS 857663-92-4)
- 3-(1H-Pyrazol-4-yl)propanenitrile hydrochloride (CAS 1431966-04-9)
- 6-Methylhept-6-en-2-one (CAS 10408-15-8)
- (3R,10S)-Heptadeca-1,8-dien-4,6-diyne-3,10-diol (CAS 708257-91-4)
- Fluorescent Red Mega 485 NHS-ester (CAS 890317-36-9)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
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