Bis(4-bromophenyl)phosphine oxide CAS 15754-53-7

Purity 97%+In StockPharmaceutical Standards
CAS No.15754-53-7
Molecular FormulaC12H9Br2OP
Molecular Weight359.98 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Bis(4-bromophenyl)phosphine oxide CAS 15754-53-7 chemical structure

Description

The occurrence of Bis(4-bromophenyl)phosphine oxide is closely related to organophosphorus functionality, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Bis(4-bromophenyl)phosphine oxide (CAS 15754-53-7), a certified reference material (molecular formula C12H9Br2OP, MW 359.98 g/mol) for analytical method development and quality control.

Structurally, Bis(4-bromophenyl)phosphine oxide (C12H9Br2OP) contains organophosphorus functionality, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 359.98 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H9Br2OP
Molecular Weight359.98 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Halogen ContentBr-containing

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