5'-Fluoro-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-quinoline] CAS 1579958-49-8
| CAS No. | 1579958-49-8 |
| Molecular Formula | C12H14FN |
| Molecular Weight | 191.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5'-Fluoro-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-quinoline] (CAS 1579958-49-8), molecular formula C12H14FN and molecular weight 191.24 g/mol, is a CATO reference standard with documented purity and traceability.
5'-Fluoro-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-quinoline] (C12H14FN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14FN |
| Molecular Weight | 191.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 6-Fluoro-3-isobutyl-1h-indole (CAS 1002332-01-5)
- 7-fluoro-2,2,4-trimethyl-1,2-dihydroquinoline (CAS 1126823-41-3)
- 7'-Fluoro-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-isoquinoline] (CAS 1283718-61-5)
- 7’-fluoro-1’,2’-dihydrospiro[cyclopentane-1,3’-indole] (CAS 1368756-19-7)
- 7-Fluoro-3-isobutyl-1h-indole (CAS 1697462-78-4)
- 5-Fluoro-3-isobutyl-1h-indole (CAS 1698727-54-6)
- 4-Fluoro-3-isobutyl-1h-indole (CAS 1774898-85-9)
- 6-Fluoro-2,2,4-trimethyl-1,2-dihydroquinoline (CAS 50772-15-1)
Recommended Standards
- 6'-Fluorospiro[cyclopentane-1,3'-indoline] (CAS 1545620-80-1)
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- (2R,5S)-2-(4-fluorophenyl)-5-vinylpyrrolidine (CAS 1389861-83-9)
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- 5-(2,5-Difluorophenyl)pyrimidin-2-ol (CAS 1111108-68-9)
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- L-Valine-13C, N-Boc (CAS 286460-61-5)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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