5-chloro-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide CAS 1580-42-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1580-42-3
Molecular FormulaC14H9ClF3NO2
Molecular Weight315.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-chloro-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide CAS 1580-42-3 chemical structure

Description

Structurally, 5-chloro-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide (C14H9ClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 315.67 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

5-chloro-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide (CAS 1580-42-3) is a high-purity analytical reference standard with the molecular formula C14H9ClF3NO2 and a molecular weight of 315.67 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-chloro-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H9ClF3NO2
Molecular Weight315.67 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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