quinoline-6-carbonyl chloride hydrochloride CAS 158000-98-7
| CAS No. | 158000-98-7 |
| Molecular Formula | C10H6ClNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of quinoline-6-carbonyl chloride hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies quinoline-6-carbonyl chloride hydrochloride (CAS 158000-98-7), a certified reference material (molecular formula C10H6ClNOHCl, MW 228.07 g/mol) for analytical method development and quality control.
The molecular framework of quinoline-6-carbonyl chloride hydrochloride (C10H6ClNOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNO HCl |
| Molecular Weight | 228.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related quinoline Standards
- Quinoline-8-carbonyl chloride (CAS 100517-41-7)
- Quinoline-6-thiol (CAS 100653-59-6)
- Quinoline-7,8-diol (CAS 101724-22-5)
- Quinoline, 7-bromo-2-hydrazinyl-3-methyl- (CAS 1017360-64-3)
- Quinoline-2,3-dicarbaldehyde (CAS 10222-53-4)
- Ethyl quinoline-7-carboxylate (CAS 104294-00-0)
- Ethyl quinoline-4-carboxylate (CAS 10447-29-7)
- Butyl quinoline-8-carboxylate (CAS 107456-13-3)
Recommended Standards
- 7-Chloro-4-[(2-chloroethyl)sulfanyl]quinoline (CAS 860196-73-2)
- (8-Bromoimidazo[1,2-a]pyridin-3-yl)methanol (CAS 1126636-98-3)
- 5-(Tert-butyl)-2-(cyclopropylmethoxy)benzaldehyde (CAS 883514-34-9)
- 2-(2-Bromo-3-(chloromethyl)-5-(difluoromethyl)pyridin-4-yl)acetic acid (CAS 1805371-88-3)
- 1-Methyl-4H-benzo[f][1,2,4]triazolo[4,3-a]azepin-6-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate (CAS 1588522-06-8)
- 3-Cyclobutyl-2-methyl-3-oxopropanenitrile (CAS 1152625-90-5)
- Methyl 2-(6-oxo-3-(phenylcarbamoyl)-5,6-dihydropyridazin-1(4H)-yl)acetate (CAS 1261000-87-6)
- 1-cyclopropyl-n-(2-methoxybenzyl)methanamine (CAS 1019561-08-0)
- 9-Benzyl-9H-purine (CAS 25491-56-9)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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