N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-5-((4-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide CAS 158712-47-1
| CAS No. | 158712-47-1 |
| Molecular Formula | C19H11F8N3OS |
| Molecular Weight | 481.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-5-((4-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide (CAS 158712-47-1), a certified reference material (molecular formula C19H11F8N3OS, MW 481.36 g/mol) for analytical method development and quality control.
The molecular framework of N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-5-((4-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide (C19H11F8N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-5-((4-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H11F8N3OS |
| Molecular Weight | 481.36 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(2,4-Difluorophenyl)-1-methyl-3-(trifluoromethyl)-5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1H-pyrazole-4-carboxamide (CAS 400086-42-2)
- N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1S,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide (CAS 1204707-73-2)
- 3-(2,4-Difluorophenyl)-1-[[1-(1-Methylindol-3-ylCyclopentyl]Methyl]-1-(Phenylmethyl)Urea (CAS 145131-57-3)
- 2,7-Bis(2,6-difluorophenyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone (CAS 1333488-67-7)
- (S)-2-(2-(3,5-Difluorophenyl)acetamido)-N-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanamide (CAS 209986-17-4)
- 1-(3,4-Difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-3-yl)oxy)-2-fluorophenyl)urea (CAS 1956311-09-3)
- 1-(3,4-Difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-2-fluorophenyl)urea (CAS 228559-81-7)
- N-(2,4-Difluorophenyl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618432-47-6)
Recommended Standards
- 2-(Boc-amino)-1-(3-bromo-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethanone (CAS 1261117-66-1)
- 2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-methoxyphenyl)ethanone (CAS 477330-83-9)
- Methyl 4-((3-(2-(acetylthio)ethyl)-2-(methoxycarbonyl)phenoxy)methyl)-2-bromobenzoate (CAS 1029720-25-9)
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(3-methoxyphenyl)ethanone (CAS 477330-29-3)
- 1,1,1-trifluoro-4-phenylbutan-2-amine hydrochloride (CAS 1432681-60-1)
- Tert-butyl (S)-((4,4-diethoxypiperidin-2-yl)methyl)carbamate fumarate (CAS 1301706-56-8)
- 6-Fluoro-2-(methylamino)pyrimidin-4(1H)-one (CAS 313961-68-1)
- 1-bromanyl-2-isothiocyanato-ethane 1-bromo-2-isothiocyanatoethane 1483-41-6 A808757 (CAS 1483-41-6)
- 3-Bromo-2,4-dimethylbenzoic acid (CAS 1255206-85-9)
- 2-(3,5-Dimethylphenyl)ethan-1-ol (CAS 62343-67-3)
- 2-(5-Chloro-2-methyl-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2377607-14-0)
- 4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide 52061-51-5 N,N-Dimethyl-|A-oxo-4-(phenylmethoxy)-1H-indole-3-acetamide (CAS 52061-51-5)
- (2R,3R,4S,5S)-2-methoxytetrahydro-2H-pyran-3,4,5-triol (CAS 3945-28-6)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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