1-(3,4-Difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-2-fluorophenyl)urea CAS 228559-81-7
| CAS No. | 228559-81-7 |
| Molecular Formula | C24H18F3N3O4 |
| Molecular Weight | 469.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3,4-Difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-2-fluorophenyl)urea is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(3,4-Difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-2-fluorophenyl)urea (CAS 228559-81-7), molecular formula C24H18F3N3O4 and molecular weight 469.41 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C24H18F3N3O4, 1-(3,4-Difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-2-fluorophenyl)urea contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 469.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(3,4-Difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-2-fluorophenyl)urea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H18F3N3O4 |
| Molecular Weight | 469.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluorophenyl Standards
- 1-(3,4-Difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-3-yl)oxy)-2-fluorophenyl)urea (CAS 1956311-09-3)
- N-(2,4-Difluorophenyl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618432-47-6)
- N-(3,4-Difluorophenyl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477330-08-8)
- N-(2,4-Difluorophenyl)-1-methyl-3-(trifluoromethyl)-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazole-4-carboxamide (CAS 282523-35-7)
- 3-(2,4-Difluorophenyl)-1-[[1-(1-Methylindol-3-ylCyclopentyl]Methyl]-1-(Phenylmethyl)Urea (CAS 145131-57-3)
- 2-(3,4-Difluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-(4-(methylsulfonyl)phenyl)pyridazin-3(2H)-one (CAS 266320-83-6)
- N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1S,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide (CAS 1204707-73-2)
- 1-(2,4-Difluorophenyl)-6-oxo-4-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)-1,6-dihydropyridazine-3-carboxamide (CAS 477859-68-0)
Recommended Standards
- 3-(((2,6-Dichlorobenzyl)thio)methyl)-4-ethyl-5-((4-nitrobenzyl)thio)-4H-1,2,4-triazole (CAS 344270-95-7)
- Ro 4929097 (CAS 847925-91-1)
- 4-(2-Bromo-9-(4-(tert-butyl)phenyl)-9H-fluoren-9-yl)phenol (CAS 849222-40-8)
- 4-Nitrophenyl 2-3-4-6-tetra-O-acetyl-β-D-glucopyranoside (CAS 5987-78-0)
- 5H-Dibenzo[b,e]azepin-6,11-dione (CAS 1143-50-6)
- (S)-Azetidine-2-carboxamide hydrochloride (CAS 648907-88-4)
- (S)-2-((S)-2-((S)-1-((S)-2-Aminopropanoyl)pyrrolidine-2-carboxamido)propanamido)propanoic acid (CAS 82748-47-8)
- (R)-3-Amino-1,2,3,4-tetrahydrocarbazole (CAS 116650-33-0)
- 1-Ethynyl-4-methylbenzene (CAS 766-97-2)
- 2-Cyanoethyltrimethoxysilane (CAS 2526-62-7)
- tert-Butyl (4-iodo-6-methoxypyridin-3-yl)carbamate (CAS 1200132-06-4)
- (3-Bromophenyl)(3-isopropylphenyl)methanol (CAS 1443352-30-4)
- N-(3-acetylphenyl)-3-amino-4,6-bis(4-chlorophenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 444157-30-6)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
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