Docetaxel Impurity 12 CAS 158810-73-2
| CAS No. | 158810-73-2 |
| Molecular Formula | C46H55Cl2NO16 |
| Molecular Weight | 948.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 948.83 g/mol gives Docetaxel Impurity 12 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Docetaxel Impurity 12 (CAS 158810-73-2, C46H55Cl2NO16) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Docetaxel Impurity 12 (C46H55Cl2NO16) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Docetaxel Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C46H55Cl2NO16 |
| Molecular Weight | 948.83 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Docetaxel Standards
- Docetaxel Impurity 46 (CAS 158810-72-1)
- Docetaxel Impurity 76 (CAS CATO-C4X-161976)
- Docetaxel Impurity 45 (CAS 1354900-65-4)
- Docetaxel Impurity 34 (CAS 1095547-96-8)
- Docetaxel Impurity 35 (CAS 1095547-98-0)
- Docetaxel Impurity 33 (CAS 95603-44-4)
- Docetaxel Impurity 10 (O-BOC N-pyruvy ldocetaxel) (CAS 1021489-55-3)
- Docetaxel Impurity 91 (CAS CATO-C4X-161991)
Recommended Standards
- Cholecystokinin, CCK (27-33) (CAS 47910-79-2)
- H-Gly-Pen-Gly-Arg-Gly-Asp-Ser-Pro-Cys-Ala-OH (Disulfide bond between Pen2 and Cys9) (CAS 126716-28-7)
- Chromium, triiodo[tris[3-(dimethylarsino)propyl]arsine]- (CAS 89655-20-9)
- IRGD (CAS 1392278-76-0)
- Ritalin Impurity 4 (CAS CATO-C4X-28814)
- Clopidogrel Impurity 79 (CAS CATO-C4X-102979)
- Faropenem Impurity 57 (CAS CATO-C4X-128957)
- Ac-D-Val-OH (CAS 17916-88-0)
- rac-3-Phenyl-pyrrolidin-2-one, 98% (CAS 6836-97-1)
- Methyl 5-chlorooctafluoropentanoate (CAS 261503-67-7)
- Ethyl 4-bromo-2-fluoronicotinate (CAS 1807176-07-3)
- 2-Thia-7-azaspiro[3.5]Nonane 2,2-dioxide (CAS 1936547-59-9)
- N-Nitroso Rosuvastatin (CAS CATO-C4X-1169211)
- Calcium-Like Peptide 3 (CAS 261969-05-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com