Docetaxel Impurity 45 CAS 1354900-65-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1354900-65-4
Molecular FormulaC51H59NO15
Molecular Weight926.01 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Docetaxel Impurity 45 CAS 1354900-65-4 chemical structure

Description

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Docetaxel Impurity 45 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 926.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Docetaxel Impurity 45 (CAS 1354900-65-4) is a certified pharmaceutical impurity reference standard with the molecular formula C51H59NO15 and a molecular weight of 926.01 g/mol.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC51H59NO15
Molecular Weight926.01 g/mol
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)23.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Nitrogen Atoms1

Related Docetaxel Standards

Recommended Standards

Why CATO?