3-Methyl-isothiazole-4-carboxylic acid CAS 15903-66-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Methyl-isothiazole-4-carboxylic acid.

3-Methyl-isothiazole-4-carboxylic acid (CAS 15903-66-9) is a high-purity analytical reference standard with the molecular formula C5H5NO2S and a molecular weight of 143.16 g/mol.

Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, 3-Methyl-isothiazole-4-carboxylic acid is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Methyl-isothiazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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