Methyl isothiazole-4-carboxylate CAS 56133-37-0
| CAS No. | 56133-37-0 |
| Molecular Formula | C5H5NO2S |
| Molecular Weight | 143.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl isothiazole-4-carboxylate.
Methyl isothiazole-4-carboxylate (CAS 56133-37-0), molecular formula C5H5NO2S and molecular weight 143.16 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, Methyl isothiazole-4-carboxylate is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl isothiazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H5NO2S |
| Molecular Weight | 143.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- Methyl isothiazole-3-carboxylate (CAS 1001907-72-7)
- 3-Methyl-isothiazole-4-carboxylic acid (CAS 15903-66-9)
- Isothiazole-5-carboxylic Acid (CAS 10271-85-9)
- Isothiazole-3-carboxylic acid (CAS 4576-90-3)
- Isothiazole-4-carboxylic acid (CAS 822-82-2)
- Ethyl isothiazole-3-carboxylate (CAS 23244-32-8)
- Isothiazole-3-carboxamide (CAS 24342-43-6)
- Isothiazole-4-carboxamide (CAS 24340-75-8)
Recommended Standards
- Methyl 2-Thiazolecarboxylate (CAS 55842-56-3)
- Pyridine-2-sulfinic acid (CAS 766445-35-6)
- alpha-Fluoromethylhistidine (CAS 69672-40-8)
- 1-Azido-4-fluorobenzene solution 3296-02-4 4-Fluorophenyl azide solution (CAS 3296-02-4)
- (4-(1-Methyl-6-(methylamino)-3,5-dinitro-1,4-dihydropyridin-2-yl)piperazin-1-yl)(phenyl)methanone (CAS 339020-83-6)
- 4-(3-chloro-4-fluorophenoxy)-3-fluorobenzonitrile (CAS 1410890-97-9)
- 2-(Butyl(phenyl)amino)ethanol (CAS 3046-94-4)
- Methyl 2-(3-chloro-5-nitropyridin-4-yl)acetate (CAS 1186087-42-2)
- 5-(Prop-2-yn-1-yl)pyrimidine-2,4(1H,3H)-dione (CAS 132400-69-2)
- (S)-1-(5-Bromopyridin-3-yl)ethan-1-ol (CAS 1108727-07-6)
- 4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 2121514-47-2)
- 3-Bromoindole-5-carboxylic Acid (CAS 916179-87-8)
- 1-[(E)-2-bromovinyl]-3,5-difluorobenzene (CAS 1260683-99-5)
- Pancreatic Polypeptide (bovine) (CAS 179986-89-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com