5-Chloro-7-methylindole-2-carboxylic Acid CAS 15936-74-0
| CAS No. | 15936-74-0 |
| Molecular Formula | C10H8ClNO2 |
| Molecular Weight | 209.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-7-methylindole-2-carboxylic Acid (CAS 15936-74-0), molecular formula C10H8ClNO2 and molecular weight 209.63 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Chloro-7-methylindole-2-carboxylic Acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 209.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-7-methylindole-2-carboxylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO2 |
| Molecular Weight | 209.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-4-hydroxy-N-(prop-2-yn-1-yl)benzamide (CAS 1019359-51-3)
- 5-Chloro-2-hydroxy-N-(prop-2-yn-1-yl)benzamide (CAS 1019359-63-7)
- 4-Chloro-2-hydroxy-N-(prop-2-yn-1-yl)benzamide (CAS 1019451-81-0)
- 5-Chloro-1-ethylindoline-2,3-dione (CAS 102838-61-9)
- 4-Chloro-6-methoxyquinolin-2(1H)-one (CAS 1029773-70-3)
- 3-Chloro-1-methyl-1h-indole-2-carboxylic acid (CAS 1043420-84-3)
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Recommended Standards
- 1-(3-chloro-4-methylphenyl)-1H-1,2,4-triazol-3-ol (CAS 1550080-15-3)
- [4-chloro-2-(1H-1,2,4-triazol-1-yl)phenyl]methanol (CAS 1597924-54-3)
- 1-(3-Chlorophenyl)pyrrolidine-2,5-dione (CAS 15386-99-9)
- 3-Chloro-4-(oxetan-3-yloxy)benzonitrile (CAS 1601843-72-4)
- Tert-butyl 2-oxa-8-azaspiro[5.5]Undecane-8-carboxylate (CAS 1889145-73-6)
- 2-(2-Chlorophenyl)-1-ethyl-1h-benzo[d]imidazole (CAS 327158-54-3)
- 4-(1,3-Dioxan-2-yl)benzaldehyde (CAS 81172-92-1)
- 2-Thioxooxazolidin-5-one (CAS 16964-95-7)
- (3-Chlorophenyl)(pyridin-2-yl)methanol (CAS 75343-75-8)
- N-benzyl-4,6-dichloropyrimidin-2(1H)-imine (CAS 76175-65-0)
- 1-(1-Methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)piperidine-4-carboxylic acid (CAS 1710845-72-9)
- 4-Amino-N,N-dimethylpiperidine-1-carboxamide Hydrochloride (CAS 873537-35-0)
- Ethyl Caffeate (CAS 102-37-4)
- Fibrinogen-Binding Inhibitor Peptide (CAS 89105-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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