5-(difluoromethoxy)quinolin-8-amine CAS 1594056-86-6
| CAS No. | 1594056-86-6 |
| Molecular Formula | C10H8F2N2O |
| Molecular Weight | 210.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(difluoromethoxy)quinolin-8-amine (C10H8F2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 5-(difluoromethoxy)quinolin-8-amine (CAS 1594056-86-6), a certified reference material (molecular formula C10H8F2N2O, MW 210.18 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8F2N2O |
| Molecular Weight | 210.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related difluoromethoxy Standards
- 8-(difluoromethoxy)quinolin-5-amine (CAS 1082893-09-1)
- 2-(Difluoromethoxy)-7-naphthol (CAS 1094284-18-0)
- 1-(Difluoromethoxy)-3-naphthol (CAS 1261600-48-9)
- 2-(Difluoromethoxy)-6-naphthol (CAS 1261600-56-9)
- 2-(Difluoromethoxy)-5-naphthol (CAS 1261787-71-6)
- 2-(Difluoromethoxy)-4-naphthol (CAS 1261813-45-9)
- 6-(Difluoromethoxy)quinolin-3-amine (CAS 2092835-40-8)
- 1,2-Bis(difluoromethoxy)benzene (CAS 27691-14-1)
Recommended Standards
- 4-[(ethoxycarbonyl)oxy]benzoic acid (CAS 15552-32-6)
- 1-(2,6-Difluorobenzyl)-1H-pyrazol-4-ol (CAS 1596958-21-2)
- (5-(2,4-Difluorophenyl)oxazol-4-yl)methanamine (CAS 1521565-01-4)
- 1-(2,5-Difluorobenzyl)-1H-pyrazol-4-ol (CAS 1597273-22-7)
- H-DL-Orn(Z)-OH (CAS 70671-51-1)
- (R)-1-(2-Fluoro-4-methoxyphenyl)ethan-1-ol (CAS 1309598-70-6)
- 4,4'-Methylenedibenzoic acid (CAS 790-83-0)
- 1,4-dibenzyl-2-(chloromethyl)piperazine (CAS 24225-89-6)
- 3-Phenylpentane-1,3,5-tricarbonitrile (CAS 16320-20-0)
- Aroclor 1016 (CAS 12674-11-2)
- 4-(Furan-2-yl)-2-hydroxybenzoic acid (CAS 1261952-89-9)
- 2-[(Cyclopentylcarbonyl)(methyl)amino]acetic acid (CAS 926252-93-9)
- tert-Butyl (1-(6-methoxypyrimidin-4-yl)piperidin-4-yl)carbamate (CAS 1353965-72-6)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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