3-(4-Fluorophenyl)-4-isoxazolecarboxylic acid ethyl ester CAS 159693-06-8
| CAS No. | 159693-06-8 |
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 235.21 g/mol gives 3-(4-Fluorophenyl)-4-isoxazolecarboxylic acid ethyl ester distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-(4-Fluorophenyl)-4-isoxazolecarboxylic acid ethyl ester (CAS 159693-06-8), a certified reference material (molecular formula C12H10FNO3, MW 235.21 g/mol) for analytical method development and quality control.
3-(4-Fluorophenyl)-4-isoxazolecarboxylic acid ethyl ester (C12H10FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(4-Fluorophenyl)-4-isoxazolecarboxylic acid ethyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 5-Ethyl-1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1017470-82-4)
- 5-Ethyl-1-(3-fluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1094311-25-7)
- Ethyl 5-(2-Fluorophenyl)isoxazole-3-carboxylate (CAS 1126636-56-3)
- Methyl 1-(2-fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate (CAS 1147207-80-4)
- 5-Ethyl-1-(2-fluorophenyl)-1h-1,2,4-triazole-3-carboxylic acid (CAS 1154370-83-8)
- [2-(4-Fluorophenyl)-4-methyl-1,3-oxazol-5-yl]acetic acid (CAS 1172370-81-8)
- 1-[2-(2-fluorophenyl)-2-oxoethyl]pyrrolidine-2,5-dione (CAS 1258652-22-0)
- Ethyl 5-(2-fluorophenyl)oxazole-4-carboxylate (CAS 127919-29-3)
Recommended Standards
- 4-Fluoro-2-((furan-2-ylmethyl)amino)benzoic acid (CAS 1518854-84-6)
- Methyl 3-(4-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 159693-09-1)
- 5-Ethyl-3-(3-fluorophenyl)isoxazole-4-carboxylic acid (CAS 1494284-72-8)
- Ethyl 1-(4-fluorophenyl)-1H-1,2,4-triazole-3-carboxylate (CAS 1613022-95-9)
- tert-Butyl 4-(5-acetylpyrimidin-2-yl)piperazine-1-carboxylate (CAS 1703794-90-4)
- ethyl(2-methylbutyl)amine (CAS 1038250-80-4)
- 1-(6-Bromo-1h-indol-3-yl)-2,2,2-trichloroethanone (CAS 188661-15-6)
- (2Z)-1-(3,4-Dichlorophenyl)-3-(dimethylamino)-2-methanesulfonylprop-2-en-1-one (CAS 344275-67-8)
- Methyl 4-chloro-3-methoxypicolinate (CAS 1255917-95-3)
- Diethyl 2,2'-(((ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(azanediyl))diacetate (CAS 866008-08-4)
- (S)-6-Fluoro-2,3-dihydrobenzofuran-3-amine (CAS 1228559-33-8)
- 1-(Tert-butylthio)cyclobutane-1-carboxylic acid (CAS 1492778-07-0)
- <I>N</I>-[[2-(diphenylphosphine)phenyl]methylene]-3-methyl-<SC>L</SC>-valine sodium salt (CAS 1067225-04-0)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
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