5-(3,3,3-Trifluoropropoxy)nicotinaldehyde CAS 1597950-96-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1597950-96-3
Molecular FormulaC9H8F3NO2
Molecular Weight219.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(3,3,3-Trifluoropropoxy)nicotinaldehyde CAS 1597950-96-3 chemical structure

Description

The occurrence of 5-(3,3,3-Trifluoropropoxy)nicotinaldehyde is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-(3,3,3-Trifluoropropoxy)nicotinaldehyde (CAS 1597950-96-3) is a high-purity analytical reference standard with the molecular formula C9H8F3NO2 and a molecular weight of 219.16 g/mol.

5-(3,3,3-Trifluoropropoxy)nicotinaldehyde (C9H8F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(3,3,3-Trifluoropropoxy)nicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H8F3NO2
Molecular Weight219.16 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Halogen ContentF-containing
Nitrogen Atoms1

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