1-(4-Phenylthiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid CAS 159885-80-0
| CAS No. | 159885-80-0 |
| Molecular Formula | C14H8F3N3O2S |
| Molecular Weight | 339.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 339.29 g/mol gives 1-(4-Phenylthiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(4-Phenylthiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 159885-80-0) is a high-purity analytical reference standard with the molecular formula C14H8F3N3O2S and a molecular weight of 339.29 g/mol.
Structurally, 1-(4-Phenylthiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (C14H8F3N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 339.29 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(4-Phenylthiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F3N3O2S |
| Molecular Weight | 339.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Phenylthiazol Standards
- Methyl 4-((4-phenylthiazol-2-yl)carbamoyl)benzoate (CAS 391876-95-2)
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- N-(4-phenylthiazol-2-yl)-2-(o-tolylthio)acetamide (CAS 338957-84-9)
- N-(4-Phenylthiazol-2-yl)-3-(phenylthio)propanamide (CAS 476307-30-9)
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- 2-((2-Phenylthiazol-5-yl)methyl)isoquinoline-1,3(2H,4H)-dione (CAS 1246961-13-6)
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- 3-(((2-Phenylthiazol-5-yl)methyl)amino)isoquinolin-1(2H)-one (CAS 1246961-09-0)
Recommended Standards
- 4-(2-(5-(Trifluoromethyl)-1H-pyrazol-1-yl)thiazol-4-yl)benzoic acid (CAS 1227954-76-8)
- 2-((2-Oxo-2-((3-(trifluoromethyl)benzyl)amino)ethyl)sulfonyl)acetic acid (CAS 338953-89-2)
- 6-(Difluoromethoxy)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 121935-03-3)
- 4-Hydroxy-N-(thiazol-2-yl)-8-(trifluoromethyl)quinoline-3-carboxamide (CAS 59197-86-3)
- 6-Fluoro-1-isopropyl-3,4-dihydronaphthalen-2(1H)-one (CAS 104204-91-3)
- 7-Chloro-4-(4-fluorobenzyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1340786-42-6)
- 1,5-naphthyridine-4-carboxylic acid (CAS 79426-14-5)
- (S)-2-Guanidino-3-(1H-imidazol-4-yl)propanoic acid (CAS 114460-37-6)
- 2,2'-(Piperazine-1,4-dicarbonyl)dibenzoic acid (CAS 195526-67-1)
- Butyl(3-nitrophenyl)sulfane (CAS 113978-49-7)
- (4-Amino-2-(tert-butylamino)thiazol-5-yl)(p-tolyl)methanone (CAS 339020-30-3)
- 1-(6-Methylpyridin-3-yl)hydrazineHCl (CAS 896133-77-0)
- (6-Bromopyridin-2-yl)(phenyl)methanol (CAS 234111-09-2)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
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