1-(4-(4-Chlorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid CAS 159885-82-2
| CAS No. | 159885-82-2 |
| Molecular Formula | C14H7ClF3N3O2S |
| Molecular Weight | 373.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 373.74 g/mol gives 1-(4-(4-Chlorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(4-(4-Chlorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 159885-82-2), a certified reference material (molecular formula C14H7ClF3N3O2S, MW 373.74 g/mol) for analytical method development and quality control.
Structurally, 1-(4-(4-Chlorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (C14H7ClF3N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 373.74 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(4-(4-Chlorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H7ClF3N3O2S |
| Molecular Weight | 373.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- Ethyl 5-(4-chlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 667920-68-5)
- 5-[(2-Chlorophenyl)sulfanyl]-4-(2,4-dichlorophenyl)-1,2,3-thiadiazole (CAS 338408-29-0)
- 5-[(2-Chlorophenyl)sulfanyl]-4-(3,4-dichlorophenyl)-1,2,3-thiadiazole (CAS 400082-16-8)
- 5-[(4-Chlorophenyl)sulfanyl]-4-(3,4-dichlorophenyl)-1,2,3-thiadiazole (CAS 400082-14-6)
- 3-(4-(3-(4-Chlorophenyl)-1H-pyrazol-5-yl)piperidin-1-yl)-1,1,1-trifluoropropan-2-ol (CAS 1030625-58-1)
- 4-Chlorophenyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazole-4-carboxylate (CAS 545399-94-8)
- Methyl 1-(4-chlorophenyl)-6-oxo-4-(pyridin-2-ylsulfanyl)-1,6-dihydropyridazine-3-carboxylate (CAS 338405-50-8)
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Recommended Standards
- N-[(1Z,3E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(methoxyimino)prop-1-en-1-yl]-4-fluoroaniline (CAS 320420-71-1)
- N-(2-Chloro-5-(trifluoromethyl)phenyl)-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide (CAS 851944-50-8)
- Bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-κN3,κO4)copper (CAS 61573-60-2)
- 2-[3-(6-Chloro-4-trifluoromethyl-pyridin-2-yl)-phenoxy]-propionic acid ethyl ester (CAS 1311278-39-3)
- 4-Cyclopropylbenzamide (CAS 1129-08-4)
- 2-Methyl-4H-imidazol-4-one (CAS 110064-77-2)
- 3-Methyl-benzamidine (CAS 18465-28-6)
- 3,3',4,5-Tetrabromodiphenyl Ether (CAS 446254-45-1)
- 4-(3-Pyrazolyl)benzonitrile (CAS 474706-35-9)
- 5-(Piperidin-1-yl)pyridin-3-amine (CAS 1314353-75-7)
- Methyl 8-bromo-6-chloro-4-hydroxyquinoline-2-carboxylate (CAS 1133116-01-4)
- Ethyl 1-(2-morpholinoethyl)-1h-pyrazole-4-carboxylate (CAS 874196-88-0)
- 8-hydrazinylquinoline (CAS 14148-42-6)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
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