1-(3,4-Dimethoxyphenyl)piperazine CAS 16015-73-9
| CAS No. | 16015-73-9 |
| Molecular Formula | C12H18N2O2 |
| Molecular Weight | 222.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3,4-Dimethoxyphenyl)piperazine (CAS 16015-73-9) is a high-purity analytical reference standard with the molecular formula C12H18N2O2 and a molecular weight of 222.28 g/mol.
1-(3,4-Dimethoxyphenyl)piperazine (C12H18N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18N2O2 |
| Molecular Weight | 222.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Dimethoxyphenyl Standards
- 1-(2,5-dimethoxyphenyl)-piperazine (CAS 1019-06-3)
- 1-(3,5-Dimethoxyphenyl)pyrrolidin-3-amine (CAS 1096807-11-2)
- (R)-2-(2,3-Dimethoxyphenyl)piperazine (CAS 1212890-13-5)
- (R)-2-(2,5-Dimethoxyphenyl)piperazine (CAS 1212929-05-9)
- (R)-2-(3,4-Dimethoxyphenyl)piperazine (CAS 1213383-80-2)
- (R)-2-(2,4-Dimethoxyphenyl)piperazine (CAS 1213466-20-6)
- (S)-2-(2,3-Dimethoxyphenyl)piperazine (CAS 1213560-79-2)
- 1-(2,5-Dimethoxyphenyl)-3-methylbutan-1-one (CAS 124557-51-3)
Recommended Standards
- tert-Butyl ((4-methylpyridin-3-yl)methyl)carbamate (CAS 1595032-33-9)
- 1-(2,4-Dimethoxyphenyl)piperazine (CAS 16015-75-1)
- 2-[5-methyl-2-(propan-2-yl)phenoxy]propanoic acid (CAS 159302-03-1)
- 2-[(Benzyloxy)methyl]-2-methylbutanoic acid (CAS 1603260-32-7)
- 1-Cyclopropyl-1h-imidazole-2-thiol (CAS 923156-13-2)
- 4-Chloro-5,6-dihydrobenzo[h]quinazoline (CAS 57711-36-1)
- 5-Fluoro-2-(isopropylamino)benzoic acid (CAS 81822-46-0)
- Trametinib impurity 04 (CAS 871700-25-3)
- 3-(4-Chlorophenyl)-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 573972-58-4)
- 2-((Ethylamino)methyl)benzonitrile (CAS 1016510-64-7)
- trans-Decahydro-quinoxaline (CAS 51773-44-5)
- 2-Acetamido-5-Picoline (CAS 4931-47-9)
- Phthalic acid, hexyl 4-methylpent-2-yl ester (CAS 109695-50-3)
- D-allo-Thr5-Semaglutide (CAS CATO-C4X-2226243)
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