1-(4-Bromophenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine CAS 16018-66-9

Purity 97%+In StockPharmaceutical Standards
CAS No.16018-66-9
Molecular FormulaC13H14BrN5
Molecular Weight320.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Bromophenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine CAS 16018-66-9 chemical structure

Description

The molecular framework of 1-(4-Bromophenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine (C13H14BrN5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

1-(4-Bromophenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine (CAS 16018-66-9), molecular formula C13H14BrN5 and molecular weight 320.19 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Bromophenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H14BrN5
Molecular Weight320.19 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Halogen ContentBr-containing
Nitrogen Atoms5

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