1-(4-Fluorophenyl)biguanide, HCl CAS 16018-83-0
| CAS No. | 16018-83-0 |
| Molecular Formula | C8H10FN5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-Fluorophenyl)biguanide, HCl is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(4-Fluorophenyl)biguanide, HCl (CAS 16018-83-0), a certified reference material (molecular formula C8H10FN5HCl, MW 231.66 g/mol) for analytical method development and quality control.
1-(4-Fluorophenyl)biguanide, HCl (C8H10FN5HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10FN5 HCl |
| Molecular Weight | 231.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Fluorophenyl Standards
- 3-[(3-fluorophenyl)methyl]pyrrolidine (CAS 1000198-80-0)
- 3-(3-Fluorophenyl)-3-oxopropanoic acid (CAS 1000530-96-0)
- Ethyl 1-(4-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000573-68-1)
- 1000574-26-4 2-(4-Fluorophenyl)-6-methylthio-4H-thiopyran-4-one MFCD09877819 (CAS 1000574-26-4)
- Ethyl 1-(2-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000575-18-7)
- 100074-04-2 5-(4-Fluorophenyl)-1-pentene MFCD11553774 (CAS 100074-04-2)
- 3-(2-Fluorophenyl)-4-hydroxyfuran-2(5H)-one (CAS 100074-44-0)
- N-[2-(4-fluorophenyl)ethyl]-1H-imidazole-1-carboxamide (CAS 1000931-75-8)
Recommended Standards
- {3-[(2-aminoethyl)(methyl)amino]propyl}dimethylamine (CAS 19475-31-1)
- 1-(3,4-Difluorophenyl)but-3-en-1-ol (CAS 1250137-60-0)
- 5-{[(4-chlorophenyl)methyl]sulfanyl}-1,3,4-thiadiazol-2-amine (CAS 72836-33-0)
- 5-(2-(1H-Imidazol-1-yl)phenyl)-1H-1,2,4-triazole (CAS 338793-57-0)
- 2-Hydroxy-2-methyl-4-oxo-4-phenylbutanoic acid (CAS 13299-97-3)
- 8-Fluoro-2-oxa-6-azaspiro[3.4]Octane-8-carboxylic acid (CAS 1936661-81-2)
- 2-Bromo-4-fluoro-5-iodobenzotrifluoride (CAS 1394291-55-4)
- 2-(3-Benzyl-7-isobutyl-2,6-dioxo-2,3,6,7-tetrahydro-1h-purin-1-yl)acetohydrazide (CAS 730951-37-8)
- Cyamemazine Tartrate (CAS 93841-82-8)
- Experimental Allergic Encephalitogenic Peptide (CAS 29705-92-8)
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