Vitamin K1 Impurity 8 CAS 16033-41-3
| CAS No. | 16033-41-3 |
| Molecular Formula | C31H46O2 |
| Molecular Weight | 450.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Vitamin K1 Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Vitamin K1 Impurity 8 (CAS 16033-41-3) is a certified pharmaceutical impurity reference standard with the molecular formula C31H46O2 and a molecular weight of 450.70 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Vitamin K1 Impurity 8 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 450.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C31H46O2 |
| Molecular Weight | 450.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Vitamin Standards
- Vitamin K1 (CAS 81818-54-4)
- Vitamin K1-18O (Mixture of 1-18O and 4-18O) (CAS 79083-00-4)
- Vitamin K1 Impurity 10 (CAS 132487-95-7)
- Vitamin K1 Impurity 11 (CAS CATO-C4X-220711)
- Vitamin K1 Impurity 12 (CAS CATO-C4X-220712)
- Vitamin K1 Impurity 13 (CAS 132487-93-5)
- Vitamin K1 Impurity 14（Z-Isomer) (CAS CATO-C4X-220714)
- Vitamin K1 Impurity 15 (CAS 132487-94-6)
Recommended Standards
- Vitamin K1 Impurity 77 (CAS CATO-C4X-220777)
- Phytomenadione/Vitamin K1 Impurity 91 (CAS CATO-C4X-220791)
- Vitamin K1 Impurity 70 (CAS 861046-93-7)
- Phytomenadione/Vitamin K1 Impurity 92 (CAS CATO-C4X-220792)
- Valproate Impurity 52 (CAS 14035-96-2)
- Mivacurium chloride Impurity 25 (CAS 104758-49-8（free base）)
- Axitinib Impurity 16 (CAS CATO-C4X-107116)
- (1S)-(-)-(7,7-Dichloro-10-camphorsulfonyl)imine (CAS 127184-04-7)
- 5,6-dichloropyridine-3-sulfonamide (CAS 622339-80-4)
- 2-(2-Chloro-4-fluorophenoxy)acetonitrile (CAS 24115-19-3)
- ethyl quinoline-5-carboxylate (CAS 98421-25-1)
- N-Cyclohexyl-3,3,5-trimethylcyclohexanamine (CAS 36132-73-7)
- Ioversol impurity 35 (CAS CATO-C4X-209135)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com