Istradefylline Impurity 2 CAS 160434-48-0

Description

Compared with other compounds in its class, the molecular weight of 370.40 g/mol gives Istradefylline Impurity 2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Istradefylline Impurity 2 (CAS 160434-48-0) is a certified pharmaceutical impurity reference standard with the molecular formula C19H22N4O4 and a molecular weight of 370.40 g/mol.

The molecular framework of Istradefylline Impurity 2 (C19H22N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com