Istradefylline Impurity 1 CAS 606080-73-3
| CAS No. | 606080-73-3 |
| Molecular Formula | C20H24N4O4 |
| Molecular Weight | 384.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Istradefylline Impurity 1 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Istradefylline Impurity 1 (CAS 606080-73-3) is a certified pharmaceutical impurity reference standard with the molecular formula C20H24N4O4 and a molecular weight of 384.43 g/mol.
Istradefylline Impurity 1 (C20H24N4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Istradefylline Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H24N4O4 |
| Molecular Weight | 384.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 4 |
Related Istradefylline Standards
- Istradefylline (CAS 155270-99-8)
- Istradefylline Impurity 22 (CAS 1453190-01-6)
- Istradefylline impurity 31 (CAS CATO-C4X-106131)
- Istradefylline Impurity 6 (CAS CATO-C4X-10616)
- Istradefylline Impurity 23 (CAS 187393-68-6)
- Istradefylline impurity 30 (CAS CATO-C4X-106130)
- Istradefylline Impurity 9 (CAS CATO-C4X-10619)
- Istradefylline Impurity 2 (CAS 160434-48-0)
Recommended Standards
- 4-(4-(4-(4-aMinophenoxy)phenoxy)phenoxy)benzenaMine (CAS 13080-88-1)
- 2-hydroxy-5-methoxybenzenecarbaldehyde N-(3-benzyl-2-quinoxalinyl)hydrazone 477888-94-1 KS-00001UT1 (CAS 477888-94-1)
- Tri-p-tolyl thiophosphate (CAS 597-84-2)
- Dabigatran Impurity 133 (CAS CATO-C4X-1089133)
- Opicapone Impurity 3 (CAS 2356241-51-3)
- Dotinurad Impurity 123 (CAS 888731-24-6)
- Rivaroxaban Impurity 184 (CAS CATO-C4X-1090184)
- 1,3-Dichloro-5-fluoro-2-(methoxymethyl)benzene (CAS 2379322-20-8)
- 24050-16-6 938P672IFL 2-Methyltetrahydrothiazole Thiazolidine, 2-methyl- 4-27-00-00661 (Beilstein Handbook Reference) BRN 0102519 Methyl-2 thiazolidine [French] 2-Methylthiazolidine Methyl-2 thiazolidine UNII-938P672IFL (CAS 24050-16-6)
- 4-Cyclobutylnicotinic acid (CAS 1554455-41-2)
- Methyl (2S)-2-[(3S)-6-chloro-2-oxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-3-yl]-2-hydroxyacetate (CAS 1638604-14-4)
- 2-(6-Fluoropyridin-3-yl)acetonitrile (CAS 337965-61-4)
- (3-Amino-2-chloropyridin-4-yl)(phenyl)methanone (CAS 342899-36-9)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com