1-((4-Chlorophenyl)amino)-4,5-dihydroxy-8-nitroanthracene-9,10-dione CAS 16058-60-9
| CAS No. | 16058-60-9 |
| Molecular Formula | C20H11ClN2O6 |
| Molecular Weight | 410.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-((4-Chlorophenyl)amino)-4,5-dihydroxy-8-nitroanthracene-9,10-dione (CAS 16058-60-9), molecular formula C20H11ClN2O6 and molecular weight 410.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-((4-Chlorophenyl)amino)-4,5-dihydroxy-8-nitroanthracene-9,10-dione (C20H11ClN2O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H11ClN2O6 |
| Molecular Weight | 410.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 1-((2-Chlorophenyl)amino)-4,5-dihydroxy-8-nitroanthracene-9,10-dione (CAS 85012-06-2)
- 1-((4-Chlorophenyl)amino)-4,8-dihydroxy-5-nitroanthracene-9,10-dione (CAS 56600-59-0)
- 3-(4-Chlorophenyl)-4-imino-6-(2-nitrophenyl)-1H,2H,3H,4H,7H,8H-[1,3]diazino[5,4-d]pyrimidine-2,8-dione (CAS 1020252-00-9)
- 5-(4-Chlorophenyl)-2-methyl-3-(4-oxo-4H-chromen-3-yl)tetrahydro-4H-pyrrolo[3,4-d]isoxazole-4,6(5H)-dione (CAS 318949-31-4)
- (E)-3-(3-(((4-chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-3-oxopropanal O-methyl oxime (CAS 303145-56-4)
- N-((2-(4-chlorophenyl)-4-methylthiazol-5-yl)methyl)-4-(trifluoromethyl)benzamide (CAS 866018-58-8)
- Methyl 2-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)acetate (CAS 1260530-41-3)
- 2-(4-(3-(4-Chlorophenyl)-6-oxopyridazin-1(6H)-yl)butanamido)benzamide (CAS 946321-13-7)
Recommended Standards
- Eldecalcitol Impurity 31 (CAS CATO-C4X-214031)
- Methyl 2-((4-amino-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)pyrimidin-2-yl)sulfonyl)acetate (CAS 1823183-25-0)
- N-(2-chloro-6-iodo-4-(trimethylsilyl)pyridin-3-yl)pivalamide (CAS 1305325-24-9)
- Heptacosanoic Acid (CAS 7138-40-1)
- 4-(Chloromethyl)-2,6-dimethylheptane (CAS 1491747-90-0)
- Methyl 2',3',4',5',6'-pentafluoro[1,1'-biphenyl]-3-carboxylate (CAS 29778-98-1)
- 1-Methyl-4-(methylamino)pyrrolidin-2-one (CAS 1453105-58-2)
- 1-(2-Aminopyrimidin-5-yl)ethan-1-one (CAS 124491-42-5)
- 3-(2-Chlorophenyl)-1H-pyrrole-2,5-dione (CAS 21724-91-4)
- 5,6-Dimethylpyridazin-3-ol (CAS 100114-19-0)
- 2-((2-Chloro-6-fluorobenzyl)oxy)-3-methylbenzaldehyde (CAS 1427026-81-0)
- (2,5-Difluorophenyl)methanesulfonyl chloride (CAS 179524-62-0)
- 5-Thia-2-azaspiro[3.4]Octane-8-carboxylic acid 5,5-dioxide (CAS 1627965-05-2)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com