4-Amino-2-(dimethylamino)phenol CAS 16058-72-3
| CAS No. | 16058-72-3 |
| Molecular Formula | C8H12N2O |
| Molecular Weight | 152.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Amino-2-(dimethylamino)phenol (CAS 16058-72-3) is a high-purity analytical reference standard with the molecular formula C8H12N2O and a molecular weight of 152.19 g/mol.
The molecular framework of 4-Amino-2-(dimethylamino)phenol (C8H12N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Amino-2-(dimethylamino)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O |
| Molecular Weight | 152.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 5-Amino-3-cyclopentylisoxazole (CAS 1012879-78-5)
- 5-Amino-1-propyl-1,2-dihydropyridin-2-one (CAS 1016767-37-5)
- 4-Amino-1-ethyl-6-methylpyridin-2(1H)-one (CAS 1082160-12-0)
- 2-Amino-4-pyridinepropanol (CAS 116598-96-0)
- 2-Amino-2-(pyridin-4-yl)propan-1-ol (CAS 1179505-80-6)
- 5-Amino-1-(propan-2-yl)-1,2-dihydropyridin-2-one (CAS 1181235-19-7)
- 2-Amino-2-(pyridin-3-yl)propan-1-ol (CAS 1183141-22-1)
- 1213040-13-1 (2S)-2-Amino-2-(6-methyl(3-pyridyl))ethan-1-ol MFCD11008539 (CAS 1213040-13-1)
Recommended Standards
- 6-Butylpyridazin-3(2H)-one (CAS 160427-25-8)
- 4-Amino-3-(dimethylamino)phenol (CAS 16058-74-5)
- 6-acetylpyridine-2-carbonitrile (CAS 159307-02-5)
- 1-(Tetrahydro-2H-pyran-2-yl)-1H-imidazole (CAS 161014-15-9)
- Tert-butyl (R)-2-methyl-3-oxopiperidine-1-carboxylate (CAS 2382079-17-4)
- 5-Cyclopropoxy-4-iodopicolinaldehyde (CAS 1243456-86-1)
- 4-((3-Aminoazetidin-1-yl)methyl)benzonitrile (CAS 1486039-35-3)
- N-(4-Methylpiperazin-1-yl)-6-(1H-1,2,4-triazol-1-yl)pyridazine-3-carboxamide (CAS 1448048-26-7)
- (S)-1-(2-Cyanoethyl)-5-oxopyrrolidine-2-carboxylic acid (CAS 41563-94-4)
- (S)-tert-Butyl 2-(2-fluorobenzyl)-3,5-dioxopyrrolidine-1-carboxylate (CAS 1313710-28-9)
- (r)-2-Amino-2-(2-methoxy-4-nitrophenyl)ethan-1-ol (CAS 1213936-76-5)
- 4-Benzoylthiophene-3-carboxylic acid (CAS 30011-77-9)
- 3-(2,3-Dihydro-1-benzofuran-7-yl)propanoic acid (CAS 1251468-51-5)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com