n-[4-cyano-5-methyl-2-oxo-3-(trifluoromethyl)-2,3-dihydro-1h-pyrrol-3-yl]benzamide CAS 634175-98-7
| CAS No. | 634175-98-7 |
| Molecular Formula | C14H10F3N3O2 |
| Molecular Weight | 309.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies n-[4-cyano-5-methyl-2-oxo-3-(trifluoromethyl)-2,3-dihydro-1h-pyrrol-3-yl]benzamide (CAS 634175-98-7), a certified reference material (molecular formula C14H10F3N3O2, MW 309.24 g/mol) for analytical method development and quality control.
n-[4-cyano-5-methyl-2-oxo-3-(trifluoromethyl)-2,3-dihydro-1h-pyrrol-3-yl]benzamide (C14H10F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10F3N3O2 |
| Molecular Weight | 309.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related n Standards
- (2E)-2-Cyano-3-(2,5-dimethoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide (CAS 1327169-32-3)
- (2E)-2-Cyano-3-(2,4-dimethoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide (CAS 1327169-48-1)
- N-(5-Cyano-2-morpholinopyrimidin-4-yl)benzamide (CAS 918662-89-2)
- Ethyl 3-cyano-7-oxabicyclo[2.2.1]heptane-2-carboxylate (CAS 1690-54-6)
- 2-Cyano-N-(4-(morpholinosulfonyl)phenyl)acetamide (CAS 379728-87-7)
- 3-Cyano-N-(3-cyano-4-methanesulfinylphenyl)benzamide (CAS 955976-81-5)
- 4-Cyano-N-(4-methoxybenzo[d]thiazol-2-yl)benzamide (CAS 313662-36-1)
- 1-(3-Cyano-6-ethylquinolin-4-yl)piperidine-4-carboxylic acid (CAS 1351804-93-7)
Recommended Standards
- N-(2-(trifluoromethyl)phenyl)benzo[d][1,3]dioxole-5-carboxamide (CAS 349415-11-8)
- (3S)-1-{[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}pyrrolidin-3-ol (CAS 1206641-40-8)
- ethyl 1-(3-cyanophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 338959-50-5)
- 6-(Benzyloxy)-8-(trifluoromethyl)-1H-purin-2-amine (CAS 160948-29-8)
- 2-Cyclopropylpyrimidin-4-ol (CAS 74649-06-2)
- tert-Butyl ethyl carbonate (CAS 27945-07-9)
- 5-(4-Tert-butylphenyl)-4-(4-methoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 713098-07-8)
- 4,7-Dimethylbenzofuran-3(2H)-one (CAS 20895-45-8)
- 5-(Bromomethyl)-1-chloro-2-ethoxy-3-fluorobenzene (CAS 1017778-91-4)
- Propargyl Ether (CAS 6921-27-3)
- (1E)-1-tert-Butoxy-1-(trimethylsilyloxy)propene (CAS 72658-10-7)
- (E)-3-(dimethylamino)-2-(2-nitrophenyl)acrylaldehyde (CAS 53868-36-3)
- 5-(1-Phenoxypropyl)-1,3,4-thiadiazol-2-amine (CAS 76784-73-1)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com