2-Chloro-5-fluoro-4-methylphenylboronic acid CAS 1612184-35-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-5-fluoro-4-methylphenylboronic acid.

2-Chloro-5-fluoro-4-methylphenylboronic acid (CAS 1612184-35-6) is a high-purity analytical reference standard with the molecular formula C7H7BClFO2 and a molecular weight of 188.39 g/mol.

The molecular framework of 2-Chloro-5-fluoro-4-methylphenylboronic acid (C7H7BClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Chloro-5-fluoro-4-methylphenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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