Sodium Cromoglicate Impurity 8 CAS 16130-28-2
| CAS No. | 16130-28-2 |
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sodium Cromoglicate Impurity 8 (CAS 16130-28-2), a pharmacopoeial impurity reference standard (molecular formula C11H12O4, MW 208.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Sodium Cromoglicate Impurity 8 (C11H12O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sodium Cromoglicate Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Sodium Standards
- Sodium Cromoglicate Impurity 13 (CAS 53878-47-0)
- Sodium Cromoglicate Impurity 9 (CAS 3361-18-0)
- Sodium Cromoglicate Impurity 10 (CAS 50521-64-7)
- Sodium Cromoglicate Impurity C51 (CAS 16130-17-9)
- Sodium Cromoglicate Impurity 12 (CAS CATO-C4X-201112)
- Cromoglicate EP Impurity A (CAS 699-83-2)
- Sodium Cromoglicate Impurity 6 (CAS 802857-44-9)
- Sodium Cromoglicate Impurity 30 (CAS CATO-C4X-201130)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com